Page 13 - JCTR-9-5

Journal of Clinical and Translational Research 2023; 9(5): 308-316

Journal of Clinical and Translational Research
Journal homepage: http://www.jctres.com/en/home

REVIEW ARTICLE

Association of appendectomy with colorectal cancer: a systematic review

and meta-analysis

Supplementary File

Table S1. Association between appendectomy and colorectal cancer
Association between appendectomy compared with CRC Number of studies included Odds ratio (95% CI)
Appendectomy versus CRC and non-CRC 8 1.30 (0.92, 1.83)
Appendectomy versus proximal and distal colon cancer 4 1.48 (1.29, 1.69)
Appendectomy versus colon and rectal cancer 6 0.96 (0.67, 1.37)
CRC: Colorectal cancer
Table S2. The Newcastle-Ottawa quality assessment scale of the included cohort studies
Author (year) Selection Comparability Outcome Total
Representativeness Selection of the Ascertainment Endpoint not Comparability Assessment Follow‑ Adequacy score
non‑ presented at (confounding) of outcome up of
exposed cohort start duration follow‑up
Abraham (2020) ★ ★ ★ ★ 0 ★ ★ 7
Friedman (1990) ★ ★ ★ ★ ★ ★ ★ 8
Lee (2018) ★ ★ ★ ★ ★ ★ ★ 8
Lee (2021) ★ ★ ★ ★ ★ ★ 0 ★ 7
Mandi (2021) ★ ★ ★ 0 ★ ★ ★ ★ 7
Shi (2021) ★ ★ ★ ★ ★ 0 ★ ★ 7
van den Boom (2021) ★ ★ ★ ★ ★ ★ ★ ★ 8
Wu (2015) ★ 0 ★ ★ ★ ★ ★ ★ 7

Table S3. The Newcastle-Ottawa quality assessment scale of the included case–control studies
Author (year) Selection Comparability Outcome Total
Representativeness Adequate Selection of Definition Comparability Assessment Method of Non‑response score
definition controls of controls of exposure assessment rate
Ergul (2009) ★ ★ ★ ★ 0 ★ ★ ★ 6

DOI: http://dx.doi.org/10.18053/jctres.09.202305.23-00090