Page 51 - MI-2-1
P. 51

Microbes & Immunity                                                    iPSC-derived NK cell immunotherapy



            121. Moreno-Nieves UY, Mundy DC, Shin JH, Tam K,   132. Shi Y, Riese DJ 2 , Shen J. The role of the CXCL12/CXCR4/
                                                                              nd
               Sunwoo   JB. The aryl hydrocarbon receptor modulates   CXCR7 chemokine axis in cancer. Front Pharmacol. 2020;
               the function of human CD56 bright  NK cells. Eur J Immunol.   11:574667.
               2018;48(5):771-776.                                doi: 10.3389/fphar.2020.574667
               doi: 10.1002/eji.201747289                      133. Muller N, Michen S, Tietze S, et al. Engineering NK cells
            122.  Zhang LH, Shin JH, Haggadone MD, Sunwoo JB. The aryl   modified with an EGFRvIII-specific chimeric antigen
               hydrocarbon receptor is required for the maintenance of liver-  receptor to overexpress CXCR4 improves immunotherapy of
               resident natural killer cells. J Exp Med. 2016;213(11):2249-2257.  CXCL12/SDF-1alpha-secreting glioblastoma. J Immunother.
                                                                  2015;38(5):197-210.
               doi: 10.1084/jem.20151998
                                                                  doi: 10.1097/CJI.0000000000000082
            123. Galley HF, Lowe PR, Carmichael RL, Webster NR. Genotype
               and interleukin-10 responses after cardiopulmonary bypass.   134.  Wirthmueller U, Kurosaki T, Murakami MS, Ravetch JV.
               Br J Anaesth. 2003;91(3):424-426.                  Signal transduction by Fc gamma RIII (CD16) is mediated
                                                                  through the gamma chain. J Exp Med. 1992;175(5):1381-1390.
               doi: 10.1093/bja/aeg174
                                                                  doi: 10.1084/jem.175.5.1381
            124. Wagage S, John B, Krock BL, et al. The aryl hydrocarbon
               receptor promotes IL-10 production by NK cells. J Immunol.   135. Barry WE, Jackson JR, Asuelime GE,  et al. Activated
               2014;192(4):1661-1670.                             natural killer cells in combination with anti-GD2 antibody
                                                                  dinutuximab improve survival of mice after surgical
               doi: 10.4049/jimmunol.1300497                      resection of primary neuroblastoma.  Clin Cancer Res.
            125. Scoville SD, Nalin AP, Chen L, et al. Human AML activates   2019;25(1):325-333.
               the aryl hydrocarbon receptor pathway to impair NK cell      doi: 10.1158/1078-0432.CCR-18-1317
               development and function. Blood. 2018;132(17):1792-1804.
                                                               136. Modak S, Le Luduec JB, Cheung IY,  et al. Adoptive
               doi: 10.1182/blood-2018-03-838474                  immunotherapy with haploidentical natural killer cells
            126. Gabriely G, Wheeler MA, Takenaka MC, Quintana FJ. Role   and Anti-GD2 monoclonal antibody m3F8 for resistant
               of AHR and HIF-1alpha in glioblastoma metabolism. Trends   neuroblastoma: Results of a phase I study. Oncoimmunology.
               Endocrinol Metab. 2017;28(6):428-436.              2018;7(8):e1461305.
               doi: 10.1016/j.tem.2017.02.009                     doi: 10.1080/2162402X.2018.1461305
            127. Daussy C, Faure F, Mayol K,  et al. T-bet and Eomes   137. Zhu H, Blum RH, Bjordahl R,  et al. Pluripotent stem
               instruct the development of two distinct natural killer cell   cell-derived  NK  cells  with  high-affinity  noncleavable
               lineages in the liver and in the bone marrow. J Exp Med.   CD16a  mediate  improved  antitumor  activity.  Blood.
               2014;211(3):563-577.                               2020;135(6):399-410.
               doi: 10.1084/jem.20131560                          doi: 10.1182/blood.2019000621
            128. Zhang J, Marotel M, Fauteux-Daniel S, et al. T-bet and eomes   138. Pattali R, Izzo K, Goncz E,  et al. 191 GAPDH knock-in
               govern differentiation and function of mouse and human NK   of high affinity CD16 in iPSC derived NK cells drives
               cells and ILC1. Eur J Immunol. 2018;48(5):738-750.  high-level  expression  and  increased  anti-tumor  function.
                                                                  J Immunother Cancer. 2021;9(Suppl 2):A203.
               doi: 10.1002/eji.201747299
                                                                  doi: 10.1136/jitc-2021-SITC2021.191
            129. Kiekens L, Van Loocke W, Taveirne S,  et al. T-BET and
               EOMES accelerate and enhance functional differentiation of   139. Hullsiek R, Li Y, Snyder KM, et al. Examination of IgG Fc
               human natural killer cells. Front Immunol. 2021;12:732511.  receptor CD16A and CD64 expression by canine leukocytes
                                                                  and their ADCC activity in engineered NK cells.  Front
               doi: 10.3389/fimmu.2021.732511                     Immunol. 2022;13:841859.
            130. Kremer V, Ligtenberg MA, Zendehdel R,  et al. Genetic      doi: 10.3389/fimmu.2022.841859
               engineering of human NK cells to express CXCR2 improves
               migration  to  renal  cell  carcinoma.  J  Immunother Cancer.   140. Snyder KM, Hullsiek R, Mishra HK, et al. Expression of a
                                                                  recombinant high affinity IgG Fc receptor by engineered NK
               2017;5(1):73.
                                                                  cells as a docking platform for therapeutic mAbs to target
               doi: 10.1186/s40425-017-0275-9                     cancer cells. Front Immunol. 2018;9:2873.
            131. Bianchi ME, Mezzapelle R. The chemokine receptor CXCR4      doi: 10.3389/fimmu.2018.02873
               in cell proliferation and tissue regeneration. Front Immunol.   141. Jing Y, Ni Z, Wu J, et al. Identification of an ADAM17 cleavage
               2020;11:2109.
                                                                  region in human CD16 (FcγRIII) and the engineering of a
               doi: 10.3389/fimmu.2020.02109                      non-cleavable version of the receptor in NK cells. PLoS One.


            Volume 2 Issue 1 (2025)                         43                               doi: 10.36922/mi.5653
   46   47   48   49   50   51   52   53   54   55   56