Page 168 - MI-2-3
P. 168

Microbes & Immunity                                                             Hyphae and healthspan



            158. Siddiqui MT, Cresci GAM. The immunomodulatory   170. Peng J, Wu Z. MTHFR act as a potential cancer biomarker
               functions of butyrate. J Inflamm Res. 2021;14:6025-6041.  in  immune  checkpoints  blockades,  heterogeneity,  tumor
                                                                  microenvironment and immune infiltration. Discov Oncol.
               doi: 10.2147/JIR.S300989
                                                                  2023;14(1):112.
            159. Ivashkiv LB. IFNγ: Signalling, epigenetics and roles in
               immunity, metabolism, disease and cancer immunotherapy.      doi: 10.1007/s12672-023-00716-0
               Nat Rev Immunol. 2018;18:545-558.               171. Reagan AM, Christensen KE, Haber A,  et al. A  common
               doi: 10.1038/s41577-018-0029-z                     risk variant in the MTHFR gene contributes to age‐related
                                                                  cerebrovascular dysfunction in VCID. Alzheimers Dement.
            160. Liu S, Ren J, Ten Dijke P. Targeting TGFβ signal transduction   2020;16:e038657.
               for cancer therapy. Sig Transduct Target Ther. 2021;6:8.
                                                                  doi: 10.1002/alz.038657
               doi: 10.1038/s41392-020-00436-9
                                                               172. Rodrigues  RR,  Gurung  M,  Li  Z,  et al.  Transkingdom
            161. Ku S, Haque MA, Jang MJ, et al. The role of Bifidobacterium   interactions between Lactobacilli and hepatic mitochondria
               in longevity and the future of probiotics. Food Sci Biotechnol.   attenuate western diet-induced diabetes.  Nat Commun.
               2024;33:2097-2110.                                 2021;12:101.
               doi: 10.1007/s10068-024-01631-y                    doi: 10.1038/s41467-020-20313-x
            162. Badal  VD, Vaccariello ED, Murray ER,  et al. The gut   173. Li M, Chi X, Wang Y, Setrerrahmane S, Xie W, Xu H.
               microbiome, aging, and longevity: A  systematic review.   Trends in insulin resistance: Insights into mechanisms and
               Nutrients. 2020;12(12):3759.                       therapeutic strategy. Sig Transduct Target Ther. 2022;7:216.
               doi: 10.3390/nu12123759                            doi: 10.1038/s41392-022-01073-0
            163. Yu R, Cao X, Sun L, et al. Inactivating histone deacetylase   174. Sohail MU, Yassine HM, Sohail A, Thani AAA. Impact of
               HDA promotes longevity by mobilizing trehalose     physical exercise on gut microbiome, inflammation, and
               metabolism. Nat Commun. 2021;12:1981.              the pathobiology of metabolic disorders. Rev Diabet Stud.
               doi: 10.1038/s41467-021-22257-2                    2019;15:35-48.
            164. Seitz HK, Stickel F. Acetaldehyde as an underestimated risk      doi: 10.1900/RDS.2019.15.35
               factor for cancer development: Role of genetics in ethanol   175. Hu D, Liu J, Yu W, et al. Tryptophan intake, not always the
               metabolism. Genes Nutr. 2010;5(2):121-128.         more the better. Front Nutr. 2023;10:1140054.
               doi: 10.1007/s12263-009-0154-1                     doi: 10.3389/fnut.2023.1140054
            165. Rehm J, Hasan OSM, Black SE, Shield KD, Schwarzinger  M.   176. Nikolic DM, Dimitrijevic-Sreckovic V, Ranin LT,  et al.
               Alcohol use and dementia: A  systematic scoping review.   Homeostatic microbiome disruption as a cause of insulin
               Alzheimers Res Ther. 2019;11(1):1.                 secretion disorders.  Candida albicans, a  new factor  in
               doi: 10.1186/s13195-018-0453-0                     pathogenesis of diabetes: A  STROBE  compliant  cross-
                                                                  sectional study. Medicine (Baltimore). 2022;101(45):e31291.
            166. Gibson A, Woodside JV, Young IS, et al. Alcohol increases
               homocysteine and reduces B vitamin concentration      doi: 10.1097/MD.0000000000031291
               in healthy male volunteers--a randomized, crossover   177. Vazquez-Munoz R, Dongari-Bagtzoglou A. Anticandidal
               intervention study. QJM. 2008;101(11):881-887.     activities by Lactobacillus Species: An update on mechanisms
               doi: 10.1093/qjmed/hcn112                          of action. Front Oral Health. 2021;2:689382.
            167. Hasan T, Arora R, Bansal AK, et al. Disturbed homocysteine      doi: 10.3389/froh.2021.689382
               metabolism is associated with cancer.  Exp Mol Med.   178. Rastogi S, Singh A. Gut microbiome and human health:
               2019;51:1-13.
                                                                  Exploring how the probiotic genus Lactobacillus modulate
               doi: 10.1038/s12276-019-0216-4                     immune responses. Front Pharmacol. 2022;13:1042189.
            168. Smith AD, Refsum H, Bottiglieri T,  et al. Homocysteine      doi: 10.3389/fphar.2022.1042189
               and dementia: An international consensus statement.   179. Korkmaz H, Sirin FB, Torus B. Could there be a role of serum
               J Alzheimers Dis. 2018;62(2):561-570.              zonulin increase in the development of hypercalcemia in
               doi: 10.3233/JAD-171042                            primary hyperparathyroidism. Endocrine. 2021;72:234-238.
            169. Hu X, Wang JB, Zhao Y, et al. Homocysteine as a trigger      doi: 10.1007/s12020-020-02504-0
               and potential therapeutic target for autoimmune diseases.   180. Lischka J, Schanzer A, Baumgartner M, de Gier C, Greber-
               Autoimmun Rev. 2023;22(9):103389.
                                                                  Platzer S, Zeyda M. Tryptophan metabolism is associated
               doi: 10.1016/j.autrev.2023.103389                  with bmi and adipose tissue mass and linked to metabolic


            Volume 2 Issue 3 (2025)                        160                               doi: 10.36922/mi.4736
   163   164   165   166   167   168   169   170   171   172   173