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Materials Science in Additive Manufacturing                             LPBF of Mg and its bio-applications



            Table 1. Comparison of physical performance between Mg alloys and other bone implants
             Materials           Density (g/cm )     Modulus (GPa)       Compressive yield (MPa)  Elongation (%)
                                          3
            Human bone [12,16,17]  1.8 – 2.1            10 – 30               130 – 180               3 – 6
            Mg alloys [16,17]      1.79 – 2.0          37.5 – 65              70 – 140               2 – 11
            Ti alloys [17,18]      4.2 – 4.5           79 – 110               795 – 908              6 – 16
            Co alloys [17,18]      8.3 – 9.2           220 – 230             450 – 1500              5 – 30
            316 L steel [17,18]      8.0                 193                  172 – 690              12 – 40
            Tantalum [17,18]         16.7              188 – 190              138 – 345              1 – 30
            Hap [18,19]              3.1               80 – 110               0.03 – 0.3               /
            TCP [18,19]               /                 24 – 39                2 – 3.5                 /
            Fe alloys [17-19]      7.8 – 7.9           200 – 205              170 – 690              12 – 40

                                                               material. Due to its characteristics, SLM can be effectively
                                                               applied as a prospective production technique for valuable
                                                               materials and components, through cutting down the
                                                               cost and lead time of fabrication and reducing the loss of
                                                               material. Therefore, it has attracted increasing interest and
                                                               attention in fabricating biodegradable Mg-based implants.
                                                                 In 2011, Ng et al.  used the SLM process to prepare
                                                                                [33]
                                                               pure Mg, which was the first report about the Mg alloy
                                                               for custom biomedical implants. Since then, Mg and its
                                                               alloys for the degradable implants has become hotspot
                                                               research in biomedical field. In this review, we present a
                                                               systematic analysis and discussion on the recent literature
                                                               on LPBF-processed Mg alloy. In addition, the effect
            Figure 1. The advantages of Mg implants and its clinical applications.
                                                               of the comprehensive powder properties, parameters
                                                               optimization,  and  post-treatment  on  their  mechanical
            the  process  has  an  extended  processing cycle  and  low   and degradable properties will be highlighted, along with
            material utilization. Unfortunately, these methods cannot   the current challenges in LPBF-processed Mg alloys. The
            easily control the pore size to obtain complex geometric   review also presents insights into the future of Mg alloys
            shapes. Additive manufacturing (AM), commonly known   and their use in biomedical applications.
            as three-dimensional (3D) printing, is a manufacturing
            technology that integrates computer-aided design,   2. LPBF-processed Mg alloys
            material processing, and molding technologies and uses
            digital model files as a basis. Meanwhile, through software   The fabrication of Mg and its alloys through LPBF is deemed
            and CNC systems, special materials are stacked layer by   to be extremely challenging. On the one hand, due to the
            layer in accordance with extrusion, sintering, melting, light   inherent inflammability and explosiveness, the preparation
            curing, or spraying to fabricate block parts . Compared   conditions of Mg powders are extremely demanding. On
                                               [31]
            with traditional manufacturing technology, AM could   the other hand, low evaporation temperature and high
            provide a reliable way to obtain personalized complex   vapor pressure of Mg tend to trigger micro-crack during
            3D structures, which can efficiently and reliably replicate   LPBF processing,  causing  poor structural integrity of
            anatomical morphology related to tissues and organs.   parts. Thus, until now, there is no relevant report on LPBF-
            It could prepare precisely controlled pore structure to   processed ultrapure Mg (>99.9%). A great deal of current
            meet the personalized customization needs of patients.   research on Mg prepared by LPBF has focused on its alloys.
            In  particular,  LPBF  is  commercially  known  as  selective   This is due to their good workability and low risk.
            laser melting (SLM), which uses metallic and non-metallic   2.1. Preparation of the feedstock
            powders as the raw material . In contrast to other AM
                                   [32]
            technologies, SLM can process a very wide variety of   It is well known that LPBF is a typical powder metallurgy
            materials. In addition, it is possible to recycle and reuse   technology. Powder properties are an essential part of
            unmelted metal powder, which allows the efficient use of the   the LPBF industry chain. The powder should possess a


            Volume 1 Issue 4 (2022)                         3                     https://doi.org/10.18063/msam.v1i4.24
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