Page 96 - OR-1-3

268. Sawai T, Hayashi Y, Niikawa T, et al. Mapping the ethical mechanical loading. Lab Chip. 2023;23:3405-342.
issues of brain organoid research and application. AJOB doi: 10.1039/d3lc00154g
Neurosci. 2022;13:81-94.
280. Sun Y, Ikeuchi Y, Guo F, Hyun I, Ming G, Fu J. Bioengineering
doi: 10.1080/21507740.2021.1896603
innovations for neural organoids with enhanced fidelity and
269. Hyun I, Scharf-Deering J, Lunshof J. Ethical issues related to function. Cell Stem Cell. 2025;32:689-709.
brain organoid research. Brain Res. 2020;1732:146653.
doi: 10.1016/j.stem.2025.03.014
doi: 10.1016/j.brainres.2020.146653
281. Jin Y, Kim J, Lee J, et al. Vascularized liver organoids
270. Lensink MA, Boers SN, Gulmans VAM, Jongsma KR, generated using induced hepatic tissue and dynamic liver-
Bredenoord AL. Mini-gut feelings: Perspectives of people specific microenvironment as a drug testing platform. Adv
with cystic fibrosis on the ethics and governance of organoid Funct Mater. 2018;28:1801954.
biobanking. Per Med. 2021;18:241-254.
doi: 10.1002/adfm.201801954
doi: 10.2217/pme-2020-0161
282. Zare Harofte S, Soltani M, Siavashy S, Raahemifar K. Recent
271. Haselager DR, Boers SN, Jongsma KR, Vinkers C, advances of utilizing artificial intelligence in lab on a chip for
Broekman ML, Bredenoord AL. Breeding brains? Patients’ diagnosis and treatment. Small. 2022;18:2203169.
and laymen’s perspectives on cerebral organoids. Regen Med.
2020;15:2351-2360. doi: 10.1002/smll.202203169
doi: 10.2217/rme-2020-0108 283. Babaliari E, Petekidis G, Chatzinikolaidou M. A precisely
flow-controlled microfluidic system for enhanced pre-
272. Kim HJ, Huh D, Hamilton G, Ingber DE. Human gut-on-a- osteoblastic cell response for bone tissue engineering.
chip inhabited by microbial flora that experiences intestinal Bioengineering (Basel). 2018;5:66.
peristalsis-like motions and flow. Lab Chip. 2012;12:2165-2174.
doi: 10.3390/bioengineering5030066
doi: 10.1039/c2lc40074j
284. Deng AF, Wang FX, Wang SC, Zhang YZ, Bai L, Su JC. Bone-
273. Habibey R, Rojo Arias J, Striebel J, Busskamp V. Microfluidics organ axes: Bidirectional crosstalk. Mil Med Res. 2024;11:37.
for neuronal cell and circuit engineering. Chem Rev.
2022;122:14842-14880. doi: 10.1186/s40779-024-00540-9
doi: 10.1021/acs.chemrev.2c00212 285. Pirosa A, Gottardi R, Alexander P, Puppi D, Chiellini F,
Tuan RS. An in vitro chondro-osteo-vascular triphasic
274. Wang H, Ning X, Zhao F, Zhao H, Li D. Human organoids-on- model of the osteochondral complex. Biomaterials.
chips for biomedical research and applications. Theranostics. 2021;272:120773.
2024;14:788-818.
doi: 10.1016/j.biomaterials.2021.120773
doi: 10.7150/thno.90492
286. Gu Y, Zhang W, Wu X, Zhang Y, Xu K, Su J. Organoid
275. Whelan IT, Burdis R, Shahreza S, Moeendarbary E, Hoey DA, assessment technologies. Clin Transl Med. 2023;13:1499.
Kelly DJ. A microphysiological model of bone development
and regeneration. Biofabrication. 2023;15:034103. doi: 10.1002/ctm2.1499
doi: 10.1088/1758-5090/acd6be 287. Dueñas ME, Peltier-Heap RE, Leveridge M, Annan RS,
Büttner FH, Trost M. Advances in high-throughput
276. Monteduro AG, Rizzato S, Caragnano G, Trapani A, mass spectrometry in drug discovery. EMBO Mol Med.
Giannelli G, Maruccio G. Organs-on-chips technologies-a 2023;15:14850.
guide from disease models to opportunities for drug
development. Biosens Bioelectron. 2023;231:115271. doi: 10.15252/emmm.202114850
doi: 10.1016/j.bios.2023.115271 288. Wu J, Yang Z, Yang B, Huang H. The application of organoids
in the research of skeletal diseases: Current status and
277. Kim SK, Kim YH, Park S, Cho SW. Organoid engineering prospects. Stud Health Technol Inform. 2023;308:597-604.
with microfluidics and biomaterials for liver, lung disease,
and cancer modeling. Acta Biomater. 2021;132:37-51. doi: 10.3233/shti230890
doi: 10.1016/j.actbio.2021.03.002 289. Stidham R, Takenaka K. Artificial intelligence for disease
assessment in inflammatory bowel disease: How will it
278. Low L, Mummery C, Berridge B, Austin C, Tagle D. Organs- change our practice? Gastroenterology. 2022;162:1493-1506.
on-chips: Into the next decade. Nat Rev Drug Discov.
2021;20:345-361. doi: 10.1053/j.gastro.2021.12.238
doi: 10.1038/s41573-020-0079-3 290. Mansoorifar A, Gordon R, Bergan R, Bertassoni LE. Bone-
on-a-chip: Microfluidic technologies and microphysiologic
279. Scheinpflug J, Hofer CT, Schmerbeck SS, et al.
A microphysiological system for studying human bone models of bone tissue. Adv Funct Mater. 2021;31:2006796.
biology under simultaneous control of oxygen tension and doi: 10.1002/adfm.202006796

Volume 1 Issue 3 (2025) 38 doi: 10.36922/OR025280024