Page 105 - TD-3-1

Tumor Discovery

CASE REPORT
Odontogenic myxofibroma arising in the

mandibular angle of a child with long-term
follow-up: A case report

1
1,2
Momoko Yoshikawa , Takeshi Karube , Hiroki Nagamine , Wataru Muraoka ,
1
1,3
1,4
Hideki Kizu , Hiromasa Kawana , Taneaki Nakagawa , and Seiji Asoda *
1
1,5
1
1 Department of Dentistry and Oral Surgery, School of Medicine, Keio University, Tokyo, Japan
2 Department of Dentistry and Oral Surgery, National Hospital Organization, Murayama Medical
Center, Tokyo, Japan
3 Department of Dentistry and Oral Surgery, Kawasaki Municipal Ida Hospital, Kawasaki, Japan
4 Department of Dentistry and Oral Surgery, Federation of National Public Service Personnel Mutual
Aid Associations, Tachikawa Hospital, Tokyo, Japan
5 Department of Oral and Maxillofacial Implantology, Kanagawa Dental University, Yokosuka, Japan

Abstract
Odontogenic myxofibroma of the jawbone is a rarity in children, and there are
few reports of cases with long-term follow-up, which mainly describe the growth
process of odontogenic myxofibroma. We herein report a case of odontogenic
myxofibroma that arose in the mandibular angle of a pediatric patient with a long-
term follow-up of more than 14 years. The patient, when he was 10-years-old, first
approached us with a complaint of painless swelling in the right mandibular angle
that was palpable and showed bone-like hardness. Computed tomography revealed
*Corresponding author: an ill-defined bone defect measuring 20 mm in diameter with bone protrusion in the
Seiji Asoda
(asoda@keio.jp) margin. A biopsy was performed to differentiate the mass from osteosarcoma, giving
a preliminary diagnosis of odontogenic myxofibroma or chondromyxofibroma.
Citation: Yoshikawa M,
Karube T, Nagamine H, et al. Therefore, tumorectomy was performed under general anesthesia. We curetted the
Odontogenic myxofibroma arising in bone surrounding the tumor and filled defect with iliac cancellous bone. The final
the mandibular angle of a child with diagnosis was odontogenic myxofibroma. At present, 14 years after the surgery, the
long-term follow-up: A case report.
Tumor Discov. 2024;3(1):2096. patient had experienced an uneventful post-operative course without recurrence.
https://doi.org/10.36922/td.2096
Received: October 24, 2023 Keywords: Odontogenic myxofibroma; Pediatric tumor; Long-term follow-up
Accepted: January 11, 2024
Published Online: March 19, 2024
Copyright: © 2024 Author(s).
This is an Open-Access article 1. Background
distributed under the terms of the
Creative Commons Attribution Odontogenic myxofibroma of the jawbone is a relatively rare disease with very few
License, permitting distribution,
1-3
and reproduction in any medium, reports regarding its occurrence in children under 10 years of age. In most cases, the
provided the original work is lesion extends to the alveolar region and is accompanied by some dental symptoms
properly cited. such as tooth deviation and movement. In addition, radiographic images may show
4
Publisher’s Note: AccScience significant bone destruction, resorption, and protrusion, which are features requiring
Publishing remains neutral with differentiation from malignant diseases such as osteosarcoma. Although post-operative
5,6
regard to jurisdictional claims in 7,8
published maps and institutional recurrence has been reported to be common, cases reporting long-term follow-up of
affiliations. the growth process remain scarce.

Volume 3 Issue 1 (2024) 1 https://doi.org/10.36922/td.2096