Page 19 - TD-3-4
P. 19

Tumor Discovery                                                        Expert consensus of NUT carcinoma





























































                                          Figure 2. Treatment types ranked by median survival time
                               Abbreviations: BET: Bromodomain and extra-terminal domain; HDAC: Histone deacetylase.

            between these regimens.                            4.1. Epidemiological characteristics

            4. Expert consensus                                The NUT carcinoma can occur at any age, with varying
                                                               median ages of onset reported across different studies.
            Eight recommendations were formulated covering the   More than 80% of NUT carcinoma patients belong to the
            entire process of diagnosing and treating NUT carcinoma   adolescent and young adult age groups, with onset ranging
            (Table S7). These recommendations address key      from newborns to 81 years of age. 15,18,29
            aspects  such  as  epidemiological  characteristics,  clinical
            manifestations, imaging findings, pathological histology   4.2. Clinical manifestations
            and  IHC  characteristics,  molecular  mechanisms  and   The clinical symptoms and laboratory test results of NUT
            subtypes, prognosis, diagnosis, and treatment.     carcinoma lack specificity,  and the disease typically
                                                                                     28


            Volume 3 Issue 4 (2024)                         11                                doi: 10.36922/td.4904
   14   15   16   17   18   19   20   21   22   23   24