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Tumor Discovery PPAR agonist and cancer
Figure 3. Effect of peroxisome proliferator-activated receptor (PPAR) agonists as an adjuvant on cell migration and invasion of cancer cells. PPAR ligand
as an adjuvant regulates the expression of E-cadherin and effects the EGFR/MAPK/PI3K-AKT pathway. This leads to decreased cell growth, cell migration,
and epithelial–mesenchymal transition in cancer cells
Figure 4. Effect of peroxisome proliferator-activated receptor (PPAR) agonists as adjuvants in inducing oxidative stress in cancer cells. PPAR ligand along
with γ-radiation activates the γ-H2AX pathway to generate reactive oxygen species, which mediates the execution of apoptosis in cancer cells
Volume 3 Issue 4 (2024) 7 doi: 10.36922/td.4003
