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Artificial Intelligence in Health





                                        ORIGINAL RESEARCH ARTICLE
                                        Diagnosis of COVID-19 from computed

                                        tomography slices using flower pollination
                                        algorithm, k-nearest neighbor, and support

                                        vector machine classifiers



                                                                                                 1
                                        Betshrine Rachel Jibinsingh 1  , Khanna Nehemiah Harichandran * ,
                                        Kabilasri Jayakannan 2  , Rebecca Mercy Victoria Manoharan 3  , and
                                        Anisha Isaac 1
                                        1 Ramanujan Computing Centre, College of Engineering Guindy,  Anna University, Chennai,
                                        Tamil Nadu, India
                                        2 Department of Information Science and  Technology, College of Engineering Guindy,  Anna
                                        University, Chennai, Tamil Nadu, India
                                        3 Department of Computer Science and Engineering, College of Engineering Guindy, Anna University,
                                        Chennai, Tamil Nadu, India



            *Corresponding author:
            Khanna Nehemiah Harichandran   Abstract
            (nehemiah@annauniv.edu)
                                        Coronavirus disease 19 (COVID-19), caused by the severe acute respiratory syndrome-
            Citation: Jibinsingh BR,
            Harichandran KN, Jayakannan  K,   coronavirus-2 virus, is commonly diagnosed through imaging techniques such as
            Manoharan RMV, Isaac A.     computed tomography (CT) scans, which reveal characteristic lung lesions. In this
            Diagnosis of COVID-19 from   study, we propose a computer-aided diagnosis (CAD) system to assist in the early
            computed tomography slices
            using flower pollination algorithm,   detection of COVID-19 from CT lung slices, leveraging advanced machine-learning
            k-nearest neighbor, and support   algorithms for precise and efficient analysis. To achieve this, we developed a CAD
            vector machine classifiers. Artif   system that diagnoses COVID-19 from CT lung slices. An adaptive Wiener filter was
            Intell Health. 2025;2(1):14-28.
            doi: 10.36922/aih.3349      applied to remove noise from the CT images. The chest tissues were then segmented
                                        using an optimal thresholding method to extract regions of interest, which represent
            Received: April 3, 2024
                                        the COVID-19 lesions under investigation.  The feature vectors were divided into
            1st revised: May 22, 2024   training and testing with  an 80/20 ratio. A  wrapper-based flower pollination
            2nd revised: June 17, 2024  algorithm was employed alongside the k-nearest neighbor classifier to select the
                                        optimal feature set.  These selected features were subsequently used to train a
            Accepted: June 24, 2024
                                        support vector machine (SVM) classifier. With feature selection, the SVM achieved
            Published Online: October 23,   an accuracy of 91.30% on a real-time dataset, outperforming seven other machine
            2024
                                        learning classifiers (radial basis function-SVM, k nearest neighbor, linear discriminant
            Copyright: © 2024 Author(s).   analysis, random forest, naïve Bayes, AdaBoost, extreme gradient boosting) and four
            This is an Open-Access article   deep learning classifiers (convolutional neural network, recurrent neural network,
            distributed under the terms of the
            Creative Commons Attribution   long short term memory, Bidirectional long short term memory). For the publicly
            License, permitting distribution,   available COVID-19 CT dataset, an accuracy of 88.18% was achieved. In conclusion,
            and reproduction in any medium,   our COVID-19 CAD system improves diagnostic accuracy, with future work aimed at
            provided the original work is
            properly cited.             enhancing efficiency and expanding to covariant detection and severity assessment.
            Publisher’s Note: AccScience
            Publishing remains neutral with   Keywords: Support vector machine; Flower pollination algorithm; k-nearest neighbor;
            regard to jurisdictional claims in
            published maps and institutional   Coronavirus disease 19; Coronavirus disease 19 computed tomography dataset
            affiliations.




            Volume 2 Issue 1 (2025)                         14                               doi: 10.36922/aih.3349
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