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Artificial Intelligence in Health Algorithm and metal oxide nanoparticle in MRI

impacting longitudinal relaxation time. In addition, References
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In contrast to the existing literature that predominantly doi: 10.1177/1051228405283362
focuses on a single type of NP, such as Fe O NPs, our
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including Co O , CuO, Fe O , NiO, and ZnO NPs. This multiple sclerosis lesion segmentation with a cascaded
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Acknowledgments lesion patterns in neuromyelitis optica spectrum disorder:
None. A pictorial review. Br J Radiol. 2018;91(1086):20170690.
doi: 10.1259/bjr.20170690
Funding
6. Zhang Y, Yang H, Zhou Z, Huang K, Yang S, Han G. Recent
This study was funded by the Brazilian agency Fundação advances on magnetic relaxation switching assay-based
de Amparo à Pesquisa do Estado de São Paulo (FAPESP nanosensors. Bioconjug Chem. 2017;28(4):869-879.
2020/03022-9, 2019/16362-5 and 2017/20032-5). doi: 10.1021/acs.bioconjchem.7b00059
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contrast agents. Adv Mater. 2009;21(21):2133-2148.
The authors declare that they have no competing interests.
doi: 10.1002/adma.200802366
Author contributions 8. Lee N, Hyeon T. Designed synthesis of uniformly sized iron

Conceptualization: Marcela de Oliveira, Marina Piacenti- oxide nanoparticles for efficient magnetic resonance imaging
Silva contrast agents. Chem Soc Rev. 2012;41(7):2575-2589.
Formal analysis: Hulder Henrique Zaparoli, Marcela de doi: 10.1039/C1CS15248C
Oliveira, Marina Piacenti-Silva 9. Bakshi R, Thompson AJ, Rocca MA, et al. MRI in multiple
Investigation: All authors sclerosis: Current status and future prospects. Lancet Neurol.
Methodology: Daniela Gomes Bornal, Hulder Henrique 2008;7(7):615-625.
Zaparoli doi: 10.1016/S1474-4422(08)70137-6
Writing – original draft: Daniela Gomes Bornal, Hulder
Henrique Zaparoli, Marcela de Oliveira 10. de Oliveira M, Gianeti TMR, da Rocha FCG, Lisboa-
Writing – review & editing: All authors Filho PN, Piacenti-Silva M. A preliminary study of the
concentration of metallic elements in the blood of patients
Ethics approval and consent to participate with multiple sclerosis as measured by ICP-MS. Sci
Rep. 2020;10(1):13112.
Not applicable.
doi: 10.1038/s41598-020-69979-9
Consent for publication 11. de Oliveira M, Piacenti-Silva M, da Rocha FCG, Santos JM,

Not applicable. Cardoso JS, Lisboa-Filho PN. Lesion volume quantification
using two convolutional neural networks in MRIs of multiple
Availability of data sclerosis patients. Diagnostics (Basel). 2022;12(2):230.

The data utilized in this study are available from the doi: 10.3390/diagnostics12020230
corresponding author on reasonable request. 12. Giacoppo S, Galuppo M, Calabrò RS, et al. Heavy metals

Volume 2 Issue 1 (2025) 64 doi: 10.36922/aih.3947