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Advanced Neurology Role of Panax ginseng in neuronal complications
MAPKs are well-reported and well-characterized Author contributions
members of the family of Ser/Thr kinases, which actively
mediate and regulate various cellular signaling pathways Conceptualization: Manal Buabeid
and external stimuli. The activation of the signaling cascade Methodology: Mizna Javed and Munaza Ijaz
of MAPK is regulated by the help of two disparate types of Resources: Manal Buabeid
cell receptors, namely, the RTKs and GCPRs, respectively. Investigation: Mizna Javed, Munaza Ijaz, and Ghulam
This cascade can effectively aid in the cell intermediate Murtaza
which is involved in cell proliferation, differentiation, and Formal analysis: Mizna Javed and Munaza Ijaz
survival. The heterogeneous members of the MAPK family Writing – original draft: Mizna Javed, Munaza Ijaz, Manal
are known to serve various biological functions, such as Buabeid
the p-42 and p-44, which are responsive to mitogenic Writing – review and editing: Ghulam Murtaza
stimuli, whereas the JNK and p-38 MAPK are responsive References
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Acknowledgments Complement Alternat Med, 2021, 5582782.
None. https://doi.org/10.1155/2021/5582782
Funding 8. Berkenblit, A, Cannistra, SA, 2005, Advances in the
management of epithelial neuronal damage. J Reprod Med,
None. 50(6): 426–438.
Conflict of interest 9. Lee, S, Rauch, J, Kolch, W, 2020, Targeting MAPK signaling
in cancer: Mechanisms of drug resistance and sensitivity. Int
The authors have no conflict of interest to declare. J Mol Sci, 21(3): 1102.
Volume 1 Issue 2 (2022) 8 https://doi.org/10.36922/an.v1i2.44

