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Advanced Neurology                                             Role of Panax ginseng in neuronal complications



              MAPKs are well-reported and well-characterized   Author contributions
            members of the family of Ser/Thr kinases, which actively
            mediate and regulate various cellular signaling pathways   Conceptualization: Manal Buabeid
            and external stimuli. The activation of the signaling cascade   Methodology: Mizna Javed and Munaza Ijaz
            of MAPK is regulated by the help of two disparate types of   Resources: Manal Buabeid
            cell receptors, namely, the RTKs and GCPRs, respectively.   Investigation: Mizna Javed, Munaza Ijaz, and Ghulam
            This cascade can effectively aid in the cell intermediate   Murtaza
            which is involved in cell proliferation, differentiation, and   Formal analysis: Mizna Javed and Munaza Ijaz
            survival. The heterogeneous members of the MAPK family   Writing – original draft: Mizna Javed, Munaza Ijaz, Manal
            are known to serve various biological functions, such as   Buabeid
            the p-42 and p-44, which are responsive to mitogenic   Writing – review and editing: Ghulam Murtaza
            stimuli, whereas the JNK and p-38 MAPK are responsive   References
            to  external  stress stimuli [52,53] . In  neurodegenerative
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              The present study has proposed the pharmacological   in the development of hepatocellular carcinoma. Genes Dev,
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            5. Conclusion                                      5.   He H, Xu J, Xu Y,  et al., 2012, Cardioprotective effects
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            Acknowledgments                                       Complement Alternat Med, 2021, 5582782.
            None.                                                 https://doi.org/10.1155/2021/5582782

            Funding                                            8.   Berkenblit, A, Cannistra, SA, 2005, Advances in the
                                                                  management of epithelial neuronal damage. J Reprod Med,
            None.                                                 50(6): 426–438.

            Conflict of interest                               9.   Lee, S, Rauch, J, Kolch, W, 2020, Targeting MAPK signaling
                                                                  in cancer: Mechanisms of drug resistance and sensitivity. Int
            The authors have no conflict of interest to declare.  J Mol Sci, 21(3): 1102.


            Volume 1 Issue 2 (2022)                         8                        https://doi.org/10.36922/an.v1i2.44
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