Page 82 - AN-2-2
P. 82

Advanced Neurology                                                    Role of immunosuppressants in autism



            100.  Illiano P, Brambilla R, Parolini C, 2020, The mutual   pathogenesis and  treatment.  Expert Rev Clin Immunol,
                interplay of gut microbiota, diet and human disease. FEBS   17: 27-35.
                J, 287: 833–855.
                                                                   https://doi.org/10.1080/1744666x.2020.1850273
                https://doi.org/10.1111/febs.15217             112.  Marçais A, Marotel M, Degouve S, et al., 2017, High mTOR
            101.  Chung J, Kuo CJ, Crabtree GR, et al., 1992, Rapamycin-  activity is a hallmark of reactive natural killer cells and
                FKBP  specifically  blocks  growth-dependent  activation   amplifies early signaling through activating receptors. Elife,
                of and  signaling  by the  70 kd  S6 protein  kinases.  Cell,   6: e26423.
                69: 1227–1236.
                                                                   https://doi.org/10.7554/elife.26423
                https://doi.org/10.1016/0092-8674(92)90643-q
                                                               113.  Marçais  A,  Cherfils-Vicini  J,  Viant  C,  et  al.,  2014,  The
            102.  Price  DJ, Grove JR, Calvo V,  et al., 1992, Rapamycin-  metabolic checkpoint kinase mTOR is essential for IL-15
                induced inhibition of the 70-kilodalton S6 protein kinase.   signaling during the  development  and activation  of  NK
                Science, 257: 973–977.                             cells. Nat Immunol, 15: 749–757.
                https://doi.org/10.1126/science.1380182            https://doi.org/10.1038/ni.2936
            103.  Li J, Kim SG, Blenis J, 2014, Rapamycin: One drug, many   114.  Nandagopal N, Ali AK, Komal AK, et al., 2014, The critical
                effects. Cell Metab, 19: 373–379.                  role of IL-15-PI3K-mTOR pathway in natural killer cell
                                                                   effector functions. Front Immunol, 5: 187.
                https://doi.org/10.1016/j.cmet.2014.01.001
                                                                   https://doi.org/10.3389/fimmu.2014.00187
            104.  Muncy J, Butler IJ, Koenig MK, 2009, Rapamycin reduces
                seizure frequency in tuberous sclerosis complex.  J  Child   115.  Ali AK, Nandagopal N, Lee SH, 2015, IL-15-PI3K-AKT-
                Neurol, 24: 477–477.                               mTOR:  A  critical pathway in  the  life  journey  of  natural
                                                                   killer cells. Front Immunol, 6: 355.
                https://doi.org/10.1177/0883073808324535
                                                                   https://doi.org/10.3389/fimmu.2015.00355
            105.  Sato A, Kasai S, Kobayashi T,  et al., 2012, Rapamycin
                reverses impaired social interaction in mouse models of   116.  Mah AY, Cooper MA, 2016, Metabolic regulation of natural
                tuberous sclerosis complex. Nat Commun, 3: 1292.   killer cell IFN-γ production. Crit Rev Immunol, 36: 131–147.
                https://doi.org/10.1038/ncomms2295                 https://doi.org/10.1615/critrevimmunol.2016017387
            106.  Chen J, Alberts I, Li X, 2014, Dysregulation of the IGF-I/  117.  Wai LE, Fujiki M, Takeda S, et al., 2008, Rapamycin, but not
                PI3K/AKT/mTOR signaling pathway in autism spectrum   cyclosporine or FK506, alters natural killer cell function.
                disorders. Int J Dev Neurosci, 35: 35–41.          Transplantation, 85: 145–149.
                https://doi.org/10.1016/j.ijdevneu.2014.03.006     https://doi.org/10.1097/01.tp.0000296817.28053.7b
            107.  Eden KE, de Vries PJ, Moss J, et al., 2014, Self-injury and   118.  Kumar S, Mehan S, Narula AS, 2022, Therapeutic
                aggression in tuberous sclerosis complex: Cross syndrome   modulation of JAK-STAT, mTOR, and PPAR-γ signaling in
                comparison and associated risk markers.  J  Neurodev   neurological dysfunctions. J Mol Med, 101: 1–41.
                Disord, 6: 10.                                     https://doi.org/10.1007/s00109-022-02272-6
                https://doi.org/10.1186/1866-1955-6-10
                                                               119.  Dreyer C, Krey G, Keller H, et al., 1992, Control of the
            108.  Tsai PT, Hull C, Chu Y, et al., 2012, Autistic-like behaviour   peroxisomal beta-oxidation pathway by a novel family of
                and cerebellar dysfunction in Purkinje cell Tsc1 mutant   nuclear hormone receptors. Cell, 68: 879–887.
                mice. Nature, 488: 647–651.
                                                                   https://doi.org/10.1016/0092-8674(92)90031-7
                https://doi.org/10.1038/nature11310
                                                               120.  Kwan V, Unda BK, Singh KK, 2016, Wnt signaling networks
            109.  Curatolo P, Moavero R, de Vries PJ, 2015, Neurological and   in autism spectrum disorder and intellectual disability.
                neuropsychiatric aspects of tuberous sclerosis complex.   J Neurodev Disord, 8: 45.
                Lancet Neurol, 14: 733–745.
                                                                   https://doi.org/10.1186/s11689-016-9176-3
                https://doi.org/10.1016/s1474-4422(15)00069-1
                                                               121.  Caracci MO, Ávila ME, De Ferrari GV, 2016, Synaptic
            110.  Tang G, Gudsnuk K, Kuo SH, et al., 2014, Loss of mTOR-  Wnt/GSK3β signaling hub in autism.  Neural Plast,
                dependent macroautophagy causes autistic-like synaptic   2016: 9603751.
                pruning deficits. Neuron, 83: 1131–1143.
                                                                   https://doi.org/10.1155/2016/9603751
                https://doi.org/10.1016/j.neuron.2014.07.040
                                                               122.  Wei J, Bhattacharyya S, Tourtellotte WG,  et  al., 2011,
            111.  Meimand SE, Rostam-Abadi Y, Rezaei N, 2020, Autism   Fibrosis in systemic  sclerosis: Emerging concepts and
                spectrum disorders and natural killer cells: A  review on   implications for targeted therapy.  Autoimmun Rev,


            Volume 2 Issue 2 (2023)                         22                         https://doi.org/10.36922/an.391
   77   78   79   80   81   82   83   84   85   86   87