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Advances in Radiotherapy
            & Nuclear Medicine                                        Mathematic modeling of PDD for FF and FFF in photon




            A                                                  A
















            B                                                   B



















                                                               Figure 3. The S  in flattening filter beams for photon energy (A) 6 and
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            Figure 2. The fitting results of percent depth dose curves of flattening   (B)  10  MV  can  be  expressed  perfectly  using  the  parameters  n  and  μ
            filter free beams for photon energies of (A) 6 and (B) 10 MV, respectively.  modeled in empirical buildup-tail function by the equation of
                                                               Sc,E = nE•(FS)0.63 μE, with nE and μE denoting the parameters n and
                                                               μ in empirical buildup-tail function at photon energy E.
            6 and 10 MV. The error in % of Table 2 and Table 3 was
            defined as follows:
                                                               the primary beam. S  is also called the in-air output ratio
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                          DPDD_B-T                           and may be defined as the ratio of the output in the air for
               Errors (%)=    DPDD    ×100%        (IV)    a given field to that for a reference field (e.g., 10 × 10 cm ).
                                                                                                            2
                                                                 S  may be approximated to a symmetric field of the same
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              Where DPDD_B-T is the dose of PDD modeled by     actual collimator opening for a dose calculation formalism
            Buildup-Tail function at a certain depth and DPDD is the   for asymmetric fields to calculate a point at the center of
            dose of measured PDD at the same depth.
                                                               an asymmetric field and a lateral distance x away from the
            4. Discussion                                      beam central axis. This approximation is a crucial role of
                                                               S  for dose calculation in radiation treatment planning
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            Figures 1 and 2 show the best fitting of FF and FFF modes   systems [17,18] .
            using the PDD  for photon energies of 6 and 10 MV,
                        b-t
            respectively. The data as shown in Table 1 indicate higher   The S  in FF beams for two photon energies can
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            photon energy resulting in higher n and lower  μ (PDD   be characterized by modeling the parameters n and  μ
            curve fitting in FF mode: n = 0.208, μ = 0.0515 for 6 MV   generated in the buildup-tail function, and the comparison
            and n = 0.495, μ = 0.0458 for 10 MV; PDD curve fitting   between modeled and measured data is shown in Table 2.
            in FFF mode: n = 0.21, μ = 0.0565 for 6 MV and n = 0.51,   Table 2 shows the measured S  in a range of 0.9709 to
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            μ = 0.0498 for 10 MV).                             1.046 for Varian 6 MV flattened photon beams and 0.9739
              The beam output (dose/MU) measured in air depends   to 1.0408  for 10 MV  flattened photon  beams at square
                                                                                    2
                                                                                                2
            on  the  field  size.  As  the  field  size  increased,  the  output   field sizes from 4 × 4 cm  to 40 × 40 cm . The deviation
            increased because of the increased S , which is added to   of  S  characterized  by Equation II  and the  measured  S
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            Volume 1 Issue 1 (2023)                         5                       https://doi.org/10.36922/arnm.0314
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