Page 63 - ARNM-1-2

Advances in Radiotherapy
& Nuclear Medicine A case of primary pulmonary FDCS

A B

C

D

E F

Figure 1. Positron emission tomography/computed tomography (PET/CT) images and analysis. (A) The PET maximum intensity projection images
revealed an avid lesion in the right lung (arrow) with several avid hilar and mediastinal lymph nodes (arrowhead) without distant metastases of other
organs. Transversal lung CT (B), PET (C), and PET/CT (D) images showed an irregular-shaped solitary pulmonary nodule (arrow) in the right superior
lobe. (E) Time activity curve of follicular dendritic cell sarcoma (FDCS) (SUV mean = 7.19), the most avid mediastinal lymph node (station 4, SUV mean = 6.84),
and normal lung (SUV mean = 0.45). (F) Patlak plot of the FDCS (K = 0.0428/min), the most avid mediastinal lymph node (K = 0.0392/min), and normal
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lung (K = 0.0007/min).
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A B C

Figure 2. Pathological evidence for follicular dendritic cell sarcoma. (A) Pathology specimen from pulmonary lesion demonstrating typical pathological
signs (H&E staining). (B) The tumor cells were positive for vimentin. (C) K-67 staining showed that the proportion of positive tumor cells was about 15%.
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Microscope magnification: ×80.

Volume 1 Issue 2 (2023) 3 https://doi.org/10.36922/arnm.0824