Page 103 - EJMO-9-1

Eurasian Journal of Medicine and
Oncology
Genomics of breast cancer in Western Kazakhstan

Table 1. Comparative analysis of allele and genotype differences between breast cancer patients and the control group
No. Polymorphism (SNP) Genotype Group (%) Total P‑value (df=1)
a
BC Control
1 Rs55886062 AA 108 (72.97) 88 (58.67) 196 0.0093
AC 40 (27.03) 62 (41.33) 102
2 Rs3918290 CC 109 (73.15) 88 (58.67) 197 0.0082
CT 40 (26.85) 62 (41.33) 102
3 Rs12721655 AA 106 (72.60) 88 (58.67) 194 0.0117
AG 40 (27.40) 62 (41.33) 102
4 Rs4987117 CC 109 (73.15) 86 (57.33) 195 0.0041
CT 40 (26.85) 64 (42.67) 104
5 Rs2229774 GG 40 (27.21) 131 (87.33) 171 <0.0001
AG 107 (72.79) 18 (12.00) 125
AA 0 (0.00)* 1 (0.67) 1
6 Rs11203289 GG 109 (73.15) 88 (58.67) 197 0.0082
GC 40 (26.85) 62 (41.33) 102
7 Rs16942 CT 75 (53.19) 94 (68.12) 169 0.0102
TT 62 (43.97) 44 (31.88) 106
CC 4 (2.84) 0 (0.00)* 4
8 Rs34945627 CC 107 (73.29) 87 (58.78) 194 0.0087
CT 39 (26.71) 61 (41.22) 100
9 Rs11571747 AA 109 (73.15) 88 (58.67) 197 0.0082
AC 40 (26.85) 62 (41.33) 102
10 Rs137852576 AG 107 (75.89) 87 (58.39) 194 0.0016
GG 34 (24.11) 62 (41.61) 96
11 Rs11571833 AA 105 (71.92) 88 (58.67) 193 0.0167
AT 41 (28.08) 62 (41.33) 103
12 Rs80359062 CC 109 (73.15) 88 (58.67) 197 0.0082
CG 40 (26.85) 62 (41.33) 102
13 Rs3218536 CC 98 (67.59) 80 (53.33) 178 0.0124
CT 47 (32.41) 70 (46.67) 117
14 Rs80357382 TT 105 (73.43) 88 (58.67) 193 0.0077
TC 38 (26.57) 62 (41.33) 100
15 Rs28934577 AA 108 (72.97) 88 (58.67) 196 0.0093
AT 40 (27.03) 62 (41.33) 102
16 Rs2981582 AG 104 (73.76) 44 (31.88) 148 <0.0001
GG 10 (7.09) 81 (58.70) 91
AA 27 (19.15) 13 (9.42) 40
17 Rs137852985 CC 33 (25.58) 136 (93.15) 169 <0.0001
TC 91 (70.54) 7 (4.79) 98
TT 5 (3.88) 3 (2.05) 8
18 Rs1800057 CC 108 (72.97) 88 (58.67) 196 0.0093
CG 40 (27.03) 62 (41.33) 102
19 Rs3092856 CC 107 (72.79) 87 (58.39) 194 0.0091
CT 40 (27.21) 62 (41.61) 102
(Cont’d...)

Volume 9 Issue 1 (2025) 95 doi: 10.36922/ejmo.5385