Page 175 - EJMO-9-1

Eurasian Journal of Medicine and
Oncology
Key signaling proteins in cardiovascular disease

doi: 10.3390/ijms21249739 Activation of Hedgehog signaling by loss of GNAS
causes heterotopic ossification. Nat Med. 2013;19(11):
48. Mondal S, Adhikari N, Banerjee S, Amin SA, Jha T. Matrix
metalloproteinase-9 (MMP-9) and its inhibitors in cancer: A 1505-1512.
minireview. Eur J Med Chem. 2020;194:112260. doi: 10.1038/nm.3314
doi: 10.1016/j.ejmech.2020.112260 55. Seidel E, Scholl UI. Genetic mechanisms of human
49. Jeunemaitre X, Soubrier F, Kotelevtsev YV, et al. Molecular hypertension and their implications for blood pressure
basis of human hypertension: Role of angiotensinogen. Cell. physiology. Physiol Genomics. 2017;49(11):630-652.
1992;71(1):169-180. doi: 10.1152/physiolgenomics.00032.2017
doi: 10.1016/0092-8674(92)90275-h 56. Matthews C, Gorenne I, Scott S, et al. Vascular smooth
50. Van Rijn JN, Hutter F. Hyperparameter Importance muscle cells undergo telomere-based senescence in human
Across Datasets. In: Proceedings of the 24 ACM SIGKDD atherosclerosis: Effects of telomerase and oxidative stress.
th
International Conference on Knowledge Discovery and Data Circ Res. 2006;99(2):156-164.
Mining. ACM; 2018. doi: 10.1161/01.RES.0000233315.38086.bc
51. Boese AC, Kim SC, Yin KJ, Lee JP, Hamblin MH. Sex 57. Liu J, Zhang C, Feng Z. Tumor suppressor p53 and its gain-
differences in vascular physiology and pathophysiology: of-function mutants in cancer. Acta Biochim Biophys Sin
Estrogen and androgen signaling in health and disease. Am (Shanghai). 2014;46(3):170-179.
J Physiol Heart Circ Physiol. 2017;313(3):H524-H545.
doi: 10.1093/abbs/gmt144
doi: 10.1152/ajpheart.00217.2016
58. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G.
52. Huang CK, Lee SO, Chang E, Pang H, Chang C. Androgen The hallmarks of aging. Cell. 2013;153(6):1194-1217.
Receptor (AR) in cardiovascular diseases. J Endocrinol.
2016;229(1):R1-R16. doi: 10.1016/j.cell.2013.05.039
doi: 10.1530/JOE-15-0518 59. Demer LL, Tintut Y. Vascular calcification: Pathobiology of
a multifaceted disease. Circulation. 2008;117(22):2938-2948.
53. Laurent MR, De Schepper J, Trouet D, et al. Consensus
recommendations for the diagnosis and management of doi: 10.1161/CIRCULATIONAHA.107.743161
X-linked hypophosphatemia in Belgium. Front Endocrinol 60. Cai J, Pardali E, Sánchez-Duffhues G, Ten Dijke P. BMP
(Lausanne). 2021;12:641543.
signaling in vascular diseases. FEBS Lett. 2012;586(14):
doi: 10.3389/fendo.2021.641543 1993-2002.
54. Regard JB, Malhotra D, Gvozdenovic-Jeremic J, et al. doi: 10.1016/j.febslet.2012.04.030

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