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Eurasian Journal of
            Medicine and Oncology                                                   Prognosis of colon adenocarcinoma



            Appendices



            A                                                B                       C














                                                               D

















            Figure A1. Identification of risk signatures for modeling sets of patients. (A) One-way Cox regression analysis identifies 12 genes associated with survival.
            (B) LASSO coefficient of the 20 selected genes. (C) Ten-fold cross-validation for tuning parameter selection in the LASSO module. (D) Overall information
            of eight genes identified using multivariate Cox proportional hazards regression in the TCGA-COAD dataset. Solid squares represent the hazard ratio of
            death.
            Abbreviations: COAD: Colon adenocarcinoma; LASSO: Least absolute shrinkage and selection operator; TCGA: The cancer genome atlas.



































            Volume 9 Issue 2 (2025)                        248                         doi: 10.36922/EJMO025060024
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