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Eurasian Journal of
            Medicine and Oncology                                    TCM regulates gut microbiota in pediatric MP pneumonia








































            Figure 5. Subgroup analysis of total clinical effectiveness.
            Notes: The effect size is presented as risk ratios (RRs) with 95% confidence intervals (CIs). The vertical line (RR=1) represents no effect. “W” stands for the
            Western medicine group; “CH” refers to the Chinese herbal medicine acupoint plaster therapy group; “C and W” denotes the group combining Western
            medicine and TCM; and “CH and W” indicates the group integrating Western medicine with Chinese herbal medicine acupoint plaster therapy.

                         A                                  B














            Figure 6. Funnel plot (A) and Egger’s test plot (B) for the comparison of the total clinical effectiveness rate of traditional Chinese medicine based on
            intestinal microbiota in the treatment of mycoplasma pneumonia, as reported in the relevant literature
            Abbreviation: RR: Risk ratio; SE: Standard error.

            Georgi may be incorporated for those with severe fever.   by intestinal microbiota in the treatment of MPP. Eleven
            Maxing Shigan Decoction  is a commonly used formula in   RCTs involving 880  children with MPP were included,
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            TCM for treating pneumonia-related diseases, and multiple   following  a  systematic  review  of  seven  national  and
            studies 30,31  have demonstrated its favorable effectiveness and   multinational databases. These 11 RCTs encompassed
            safety.                                            treatments commonly used for MPP in both Chinese and
                                                               Western medicine, including tonics such as Ma Xing Shi
            4. Discussion                                      Gan Tang, antipyretic drugs combined with  antibiotics,

            This study aimed to further validate the potential   and symptomatic treatments. The meta-analysis confirmed
            effectiveness and safety of Chinese medicine modulated   that Chinese medicine modulated by the intestinal


            Volume 9 Issue 2 (2025)                         50                              doi: 10.36922/ejmo.8602
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