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Global Health Econ Sustain                                                    Implication of close contact



            number of direct interactions among individuals (Murray,   birth rate required in these models is significantly higher
            2002).  However,  the  key  elements  facilitating  the  rapid   than the actual birth rate in the respective regions. For
            spread of COVID-19 were the variability of possible   example, Chile has a birth rate of approximately 12 births
            symptoms and the pre-symptomatic infectivity (He et al.,   per year per 1000 people. On the other hand, the stationary
            2020). Consequently, an undetected number of infective   daily case rate was around 1700 cases per day in the Region
            individuals may have been amplifying the epidemic   Metropolitana (the most populated region, where Santiago
            within their community and even potentially exporting   de Chile is located) between August and November 2020,
            the infection to other regions without realizing that they   which equates to an estimated 110  cases per year per
            were ill. For symptomatic individuals, COVID-19 exhibits   1000 people, far surpassing the rate of new susceptible
            higher contagiousness around the time of symptom onset   individuals needed to maintain a stable epidemic.
            (around 5 days after acquiring the infection); however, the   Other authors have incorporated time-dependent
            infectivity gradually decreases and reaches zero within   variables into their models, which were adjusted to
            an average of 10–15  days (He  et al., 2020; Rhee  et al.,   reproduce clinical data (Zhao & Chen, 2020; Bagal et al.,
            2021). Therefore, promptly identifying any asymptomatic   2020;  El  Fatini  et  al.,  2021).  These  models  account  for
            spreaders among the close contacts of symptomatic   various stages of epidemics and consider variations in the
            individuals can significantly mitigate the impact of the   strength of quarantine policy. As a result, they predicted
            epidemic (Kwon  et al., 2020). Initial analysis suggested   that the epidemic would subside within a couple of months
            that successfully tracing 70% of contacts (approximately   and not exhibit an equilibrium evolution. However, Choi
            36 people in the United Kingdom) could be an effective   & Ki (2020) were able to achieve an equilibrium behavior
            strategy for containing an outbreak (Anderson et al., 2020).  modeling the evolution of the epidemic in South Korea by

              South  Korea was one of the first countries outside   adjusting the model parameters in five different intervals
            China to experience the impact of the COVID-19 epidemic   and selecting a value close to 1 for the basic reproductive
            (Shim et al., 2020). To control the spread of the disease,   rate at equilibrium.
            various non-pharmaceutical mitigation measures were   We acknowledge that certain parameters in epidemic
            implemented, including some controversial approaches,   models are time-dependent due to variations in people’s
            such as the extensive use of information technology to   activity during different public health policies. However,
            trace contacts (Park  et al., 2020). These measures make   we believe that the prolonged stationary behavior (lasting
            South Korea an excellent case for analysis. In this respect,   more than 100  days in South  Korea) cannot be solely
            several different models have been considered to describe   attributed to an  exact  compensation between epidemic
            the evolution of the disease in different countries, including   evolution and people’s interactions. Moreover, data
            South Korea, with the aim of predicting the timing and   analysis indicates the existence of three different stationary
            magnitude of the peak of the epidemic (Adam, 2020).   stages for daily COVID-19  cases in South  Korea. The
            These  models  include  individual-based  network  models   analysis suggests the presence of a mechanism that leads
            (Son  &  Team,  2020;  Ferguson  et al.,  2020)  and  simpler   to  equilibrium  through  competition  between  different
            compartmental models (CMs) (Wang  et al., 2020; Reis   processes. In this respect, we consider that this epidemic
            et al., 2020).                                     behavior is a result of a balance between the spread of
              Compartmental models are utilized by assuming a fast-  disease and the government policies implemented to
            mixed and homogeneous population where all individuals   control it, particularly the intensive search for cases among
            have the potential to come into contact with one another.   close contacts of newly infected individuals. In this regard,
            In this context, South Korea or New York City serves as   South Korea, once again, provides an excellent case study
            excellent examples of applying a CM. However, while   due to its strong campaign of mass testing and contact
            many studies have employed CMs to analyze the spread   tracing of infected individuals (Park  et al., 2020; Kim
            of COVID-19 in South  Korea (Kim  et al., 2020; Magal   et al., 2020).
            & Webb, 2020), these models fail to accurately capture   The outbreak of coronavirus has not only triggered
            the long stationary phase observed between April and   a global crisis but has also introduced an epidemic with
            August 2020, preceding the second wave of the pandemic   new characteristics that have made it challenging to halt
            (Worldometers.info, 2021). Similar behavior has been   its spread. First, there is a wide spectrum in the disease
            observed in diverse regions (cities or countries) such as   severity, ranging from asymptomatic individuals to those
            New York City or Chile. Some researchers have incorporated   resulting in fatalities. Second, individuals infected with
            birth and death processes into their models to account for   the virus become contagious before the appearance of
            this stationary phase (Wang  et al., 2020). However, the   symptoms or even without ever exhibiting any symptoms.


            Volume 1 Issue 1 (2023)                         2                        https://doi.org/10.36922/ghes.0873
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