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Global Health Economics and
            Sustainability
                                                                     Hospitalizations due to obesity and deaths from diabetes


              When analyzing the correlation between hospitalizations   collecting data, a lack of clarity regarding the importance
            for obesity and deaths from T2DM, we can consider obesity   of this variable, or challenges faced by the participants in
            a significant risk factor for individuals with T2DM. Several   self-identifying their color or race, often due to pre-judice
            correlations in this study are supported by other research,   or a lack of awareness. This situation may be particularly
            confirming that obesity is closely associated with one of   relevant in the case of self-reported classifications of “non-
            the most prevalent diseases in modern society – T2DM.   white,” which can carry negative social connotations,
            For example, when BMI (kg/m ) exceeds 35, the risk of   particularly for Black individuals (Araújo, 2016).
                                      2
            developing T2DM increases by 93  times in women and   Moreover,  research  indicates  that  the  prevalence  of
            42 times in men. The health risks associated with obesity
            increase progressively and disproportionately with weight   hypertension among Black women is up to 130% higher
            gain, in what is known as the “J” curve. Furthermore,   compared to White women. This disparity is linked to
            obesity  exacerbates  mortality  risks  (Pinho  et al.,  2013).   several factors, including genetic pre-disposition, poorer
            In the same study (Pinho et al., 2013), it was found that   living conditions, limited access to healthcare, and higher
            approximately 75% of non-insulin-dependent diabetic   levels of stress (Malta et al., 2017).
            patients are overweight. A  10% increase in body weight   Given the increasing prevalence of T2DM and its chronic
            results in a 2  mg/dL increase in fasting blood glucose.   complications throughout the state, it is important for
            Moreover, studies have shown that a waist circumference   public authorities to invest in improving access to reliable
            greater than 100 cm can increase the risk of developing   information about the determinants and consequences of
            T2DM  by  3.5  times,  even  after  controlling  for  BMI   overweight. This effort includes developing comprehensive
            (Franchischi et al., 2000).                        public policies aimed at fostering healthy choices in diet
              In the development of T2DM, the adipose tissue   and physical activity across all social classes.
            increases the demand for insulin, and in obese patients,   Regions with the highest rates of overweight and obesity,
            it can create insulin resistance, leading to elevated blood   such as Rio Branco, Cruzeiro do Sul, and Sena Madureira,
            sugar levels and subsequent hyperinsulinemia. However,   should be targeted for specific interventions focused on
            the sensitivity of adipose tissue to insulin may remain   preventing T2DM and promoting healthy lifestyle habits.
            high, suggesting that lipogenesis may still be favored. In   In addition, younger age groups should be prioritized, as
            some cases, this resistance may be attributed to a decrease   they are at the highest risk for developing T2DM related to
            in insulin receptor concentrations or a failure in the   overweight and obesity.
            cellular transport mechanisms (Franchischi et al., 2000).
            This mechanism may help explain the absence of data   5. Conclusion
            on obesity-related deaths, as deaths might be reported   Our findings reveal a significant increase in deaths due
            under different risk factors. It is also worth mentioning   to T2DM over the study period, accompanied by rising
            that, according to DATASUS, the cause of hospitalization   hospital costs. The data also show a higher prevalence
            is the primary diagnosis listed, directly transcribed from
            the medical record by the registration service units. Since   of T2DM in older age groups, with a relatively balanced
            obesity can be the underlying cause of multiple diseases,   distribution between men and women. Regarding obesity,
            the primary diagnosis reported in the medical record may   hospitalizations were more  frequent in  individuals  aged
            focus  on life-threatening conditions rather  than  obesity   30 and older, particularly among women. Furthermore,
            itself (Cascão et al., 2016).                      a notable correlation was found between T2DM-related
                                                               deaths and hospitalizations due to obesity, suggesting
              In general, this study has shown that the incidence of   that many T2DM-related deaths occurred in individuals
            type 2 diabetes and obesity has been higher in the female   also hospitalized for obesity, a condition that is associated
            population compared to the male population.        with various comorbidities. In summary, we recommend
              This result is expected, as women are generally more   further studies on this topic to inform the development
            proactive in managing their health and maintaining better   of more effective and targeted public health policies to
            control over their blood pressure levels than men. Women   address these interconnected health issues.
            are more likely to visit health services and adhere to
            treatment regimens, while men, for cultural reasons, tend   Acknowledgments
            to avoid seeking medical assistance and taking care of their   None.
            health (Dantas et al., 2017).
              The lack of information on race/skin color may be   Funding
            attributed to difficulties faced by the interviewers in   None.


            Volume 3 Issue 2 (2025)                        110                       https://doi.org/10.36922/ghes.3027
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