Page 113 - GPD-3-2
P. 113

Gene & Protein in Disease                                                   Inhibition of SOD1 in diseases



               dismutase 1. Clin Cancer Res. 2006;12(16):4974-4982.  of the ROS signaling network.  Oxid Med Cell Longev.
                                                                  2019;2019:9706792.
               doi: 10.1158/1078-0432.CCR-06-0171
            37.  Fatoki TH, Awofisayo OA, Ibraheem O, Oyedele AS, Akinlolu      doi: 10.1155/2019/9706792
               OS. In silico investigation of first-pass effect on selected small   42.  Wong F, Krishnan A, Zheng EJ,  et al. Benchmarking
               molecule excipients and structural dynamics of P-glycoprotein.   AlphaFold-enabled molecular docking predictions for
               Bioinform Biol Insights. 2020;14:1177932220943183.  antibiotic discovery. Mol Syst Biol. 2022;18(9):e11081.
               doi: 10.1177/11779322209431                        doi: 10.15252/msb.202211081
            38.  Martin P, Giardiello M, McDonald TO, Rannard SP, Owen A.   43.  Huang HJ, Chang TT, Chen HY, Chen CY. Finding inhibitors
               Mediation of in vitro cytochrome P450 activity by common   of mutant superoxide dismutase-1 for amyotrophic lateral
               pharmaceutical excipients. Mol Pharm. 2013;10:2739-2748.  sclerosis therapy  from traditional Chinese medicine.  Evid
               doi: 10.1021/mp400175n                             Based Complement Alternat Med. 2014;2014:156276.
            39.  Antonyuk S, Strange RW, Hasnain SS. Structural discovery      doi: 10.1155/2014/156276
               of small molecule binding sites in Cu-Zn human superoxide   44.  Fatoki TH. Human adenovirus DNA polymerase is
               dismutase familial amyotrophic lateral sclerosis mutants   evolutionarily and functionally associated with human
               provides insights for lead optimization.  J  Med Chem.   telomerase reverse transcriptase based on in silico molecular
               2010;53(3):1402-1406.                              characterization that implicate abacavir and zidovudine.
               doi: 10.1021/jm9017948                             Front Bioinform. 2023;3:1123307.
            40.  Li S, Fu L, Tian T, et al. Disrupting SOD1 activity inhibits cell      doi: 10.3389/fbinf.2023.1123307
               growth and enhances lipid accumulation in nasopharyngeal   45.  Fatoki  TH,  Balogun  CT,  Oluwadare  OT,  et al.  In silico
               carcinoma. Cell Commun Signal. 2018;16:28.         evaluation  of  nutri-pharmacological  potentials  of
               doi: 10.1186/s12964-018-0240-3                     phytochemicals in sorghum (Sorghum bicolor) grains.
                                                                  J Food Bioact. 2023;23:18354.
            41.  Li X, Chen Y, Zhao J, et al. The specific inhibition of SOD1
               selectively promotes apoptosis of cancer cells via regulation      doi: 10.31665/JFB.2023.18354











































            Volume 3 Issue 2 (2024)                         12                              doi: 10.36922/gpd.3042
   108   109   110   111   112   113   114   115   116   117   118