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Gene & Protein in Disease The effect of myostatin on muscle-related miRNAs

Funding 2006;38(7):813-818.

This work was supported by the National Natural Science doi: 10.1038/ng18106
Foundation of China (Grant No. 2023YFD2400302), the 6. Mosher DS, Quignon P, Bustamante CD, et al. A mutation
Key Research and Development Program Project of Anyang in the myostatin gene increases muscle mass and enhances
(Grant No. 2023C01SF172), and the Postdoctoral Research racing performance in heterozygote dogs. PLoS Genet.
Start-up Project of Anyang Institute of Technology (Grant 2007;3(5):e79.
No. BHJ2021003). doi: 10.1371/journal.pgen.0030079

Conflict of interest 7. Wang K, Tang X, Xie Z, et al. CRISPR/Cas9-mediated
knockout of myostatin in Chinese indigenous Erhualian
The authors declare no competing interests. pigs. Transgenic Res. 2017;26(6):799-805.

Author contributions doi: 10.1007/s11248-017-0044-z
Conceptualization: Shaoting Weng, Yao Wang 8. Schuelke M, Wagner KR, Stolz LE, et al. Myostatin mutation
associated with gross muscle hypertrophy in a child. N Engl
Formal analysis: Kaiqi Lian, Kunpeng Zhang J Med. 2004;350(26):2682-2688.
Investigation: Ruifeng Chen, Liqiang Wang, Sen Lin
Methodology: Shengming Ma, Wenhui Zhang, Zhongyi Luo doi: 10.1056/NEJMoa040933
Writing – original draft: Shaoting Weng 9. Cui Y, Yi Q, Sun W, et al. Molecular basis and therapeutic
Writing – review & editing: Xinying Ji, Yao Wang potential of myostatin on bone formation and metabolism
in orthopedic disease. Biofactors. 2023;49(1):21-31.
Ethics approval and consent to participate
doi: 10.1002/biof.1675
Not applicable.
10. Cai C, Qian L, Jiang S, et al. Loss-of-function myostatin
Consent for publication mutation increases insulin sensitivity and browning of white
fat in Meishan pigs. Oncotarget. 2017;8(21):34911-34922.
Not applicable. doi: 10.18632/oncotarget.16822

Availability of data 11. Lee SJ. Targeting the myostatin signaling pathway to treat
muscle loss and metabolic dysfunction. J Clin Invest.
The data that support the findings of this study are available 2021;131(9):e148372.
from the corresponding author upon reasonable request.
doi: 10.1172/JCI148372
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