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Gene & Protein in Disease                                              Perineural invasion in prostate cancer



            Acknowledgments                                       doi: 10.1016/j.oraloncology.2008.11.015

            None.                                              6.   de Carvalho Fraga CA, Farias LC, de Oliveira MVM, et al.
                                                                  Increased VEGFR2 and MMP9 protein levels are associated
            Funding                                               with epithelial dysplasia grading.  Pathol Res Pract.
                                                                  2014;210:959-964.
            None.
                                                                  doi: 10.1016/J.PRP.2014.06.020
            Conflict of interest                               7.   Poswar FDO, Fraga CADC, Gomes ESB,  et al. Protein
                                                                  expression of MMP-2 and MT1-MMP in actinic keratosis,
            The authors declare that they have no competing interests.  squamous cell carcinoma of the skin, and basal cell
            Author contributions                                  carcinoma. Int J Surg Pathol. 2015;23:20-25.
                                                                  doi: 10.1177/1066896914540998
            Conceptualization: All authors
            Formal analysis: All authors                       8.   Hingorani DV, Lippert CN, Crisp JL, et al. Impact of MMP-2
                                                                  and MMP-9 enzyme activity on wound healing, tumor
            Investigation: All authors                            growth and RACPP cleavage. PLoS One. 2018;13:e0198464.
            Methodology: All authors
            Writing–original draft: All authors                   doi: 10.1371/journal.pone.0198464
            Writing–review & editing: All authors              9.   Huang CY, Chang YM, Shih YT,  et al. Schwann cell
                                                                  migration induced by earthworm extract via activation of
            Ethics approval and consent to participate            PAs and MMP2/9 mediated through ERK1/2 and p38. Evid
                                                                  Based Complement Alternat Med. 2011;2011:395458.
            Not applicable.
                                                                  doi: 10.1093/ecam/nep131
            Consent for publication                            10.  Deborde S, Omelchenko T, Lyubchik A, et al. Schwann cells
            Not applicable.                                       induce cancer cell dispersion and invasion.  J  Clin Invest.
                                                                  2016;126:1538-1554.
            Availability of data                                  doi: 10.1172/JCI82658
            Data are available from the corresponding author upon   11.  Fraga CADC, De Oliveira MVM, De Oliveira ES,  et al.
            reasonable request.                                   A high HIF-1α expression genotype is associated with poor
                                                                  prognosis of upper aerodigestive tract carcinoma patients.
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            Volume 3 Issue 3 (2024)                         10                              doi: 10.36922/gpd.3146
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