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Gene & Protein in Disease Gene fusions and chimeric RNAs

doi: 10.1038/ng0608-685 between Japanese and German women--a pilot study. J
Dermatol Sci. 2011;62:138-140.
3. Nowell P. The minute chromosome (Phl) in chronic
granulocytic leukemia. Blut. 1962;8:65-66. doi: 10.1016/j.jdermsci.2011.02.010
doi: 10.1007/BF01630378 14. Gisselsson D, Pettersson L, Höglund M, et al. Chromosomal
breakage-fusion-bridge events cause genetic intratumor
4. Rowley JD. A new consistent chromosomal abnormality in
chronic myelogenous leukaemia identified by quinacrine heterogeneity. Proc Natl Acad Sci U S A. 2000;97:5357-5362.
fluorescence and Giemsa staining. Nature. 1973;243:290- doi: 10.1073/pnas.090013497
293.
15. Ally A, Balasundaram M, Carlsen R, et al. Comprehensive
doi: 10.1038/243290a0 and integrative genomic characterization of hepatocellular
carcinoma. Cell. 2017;169:1327-1341.e1323.
5. Rowley JD. The critical role of chromosome translocations
in human leukemias. Annu Rev Genet. 1998;32:495-519. doi: 10.1016/j.cell.2017.05.046
doi: 10.1146/annurev.genet.32.1.495 16. Northcott PA, Shih DJ, Peacock J, et al. Schumacher,
Subgroup-specific structural variation across 1,000
6. Shtivelman E, Lifshitz B, Gale RP, Canaani E. Fused
transcript of abl and bcr genes in chronic myelogenous medulloblastoma genomes. Nature. 2012;488:49-56.
leukaemia. Nature. 1985;315:550-554. doi: 10.1038/nature11327
doi: 10.1038/315550a0 17. Teles Alves I, Hiltemann S, Hartjes T, et al. Gene fusions by
chromothripsis of chromosome 5q in the VCaP prostate
7. Tuna M, Amos CI, Mills GB. Molecular mechanisms and
pathobiology of oncogenic fusion transcripts in epithelial cancer cell line. Hum Genet. 2013;132:709-713.
tumors. Oncotarget. 2019;10:2095. doi: 10.1007/s00439-013-1308-1
doi: 10.18632/oncotarget.26777 18. Efanov AA, Brenner AV, Bogdanova TI, et al. Investigation of
the relationship between radiation dose and gene mutations
8. Chwalenia K, Facemire L, Li H. Chimeric RNAs in cancer and fusions in post-Chernobyl thyroid cancer. J Natl Cancer
and normal physiology. Wiley Interdiscip Rev RNA.
2017;8:e1427. Inst. 2018;110:371-378.
doi: 10.1093/jnci/djx209
doi: 10.1002/wrna.1427
19. Su X, Li Z, He C, Chen W, Fu X, Yang A. Radiation exposure,
9. Zhang Y, Gong M, Yuan H, Park HG, Frierson HF, Li H.
Chimeric transcript generated by cis-splicing of adjacent young age, and female gender are associated with high
genes regulates prostate cancer cell proliferation. Cancer prevalence of RET/PTC1 and RET/PTC3 in papillary
Discov. 2012;2(7):598-607. thyroid cancer: A meta-analysis. Oncotarget. 2016;7:16716.
doi: 10.18632/oncotarget.7574
doi: 10.1158/2159-8290.CD-12-0042
20. Leeman‐Neill RJ, Kelly LM, Liu P, et al. ETV6‐NTRK3
10. Soda M, Choi YL, Enomoto M, et al. Identification of the
transforming EML4-ALK fusion gene in non-small-cell is a common chromosomal rearrangement in radiation‐
lung cancer. Nature. 2007;448:561-566. associated thyroid cancer. Cancer. 2014;120:799-807.
doi: 10.1002/cncr.28484
doi: 10.1038/nature05945
21. Dacic S, Luvison A, Evdokimova V, et al. RET rearrangements
11. Li Y, Li Y, Yang T. Clinical significance of EML4-ALK fusion
gene and association with EGFR and KRAS gene mutations in lung adenocarcinoma and radiation. J Thorac Oncol.
in 208 Chinese patients with non-small cell lung cancer. 2014;9:118-120.
PLoS One. 2013;8:e52093. doi: 10.1097/JTO.0000000000000015
doi: 10.1371/journal.pone.0052093 22. Chen Y, Li G, Lei Y, et al. Lung cancer family history and
exposure to occupational/domestic coal combustion
12. Hermans KG, Van Marion R, Van Dekken H, Jenster G,
Van Weerden WM, Trapman J. TMPRSS2: ERG fusion by contribute to variations in clinicopathologic features and
translocation or interstitial deletion is highly relevant in gene fusion patterns in non‐small cell lung cancer. Thorac
androgen-dependent prostate cancer, but is bypassed in late- Cancer. 2019;10:695-707.
stage androgen receptor-negative prostate cancer. Cancer doi: 10.1111/1759-7714.12987
Res. 2006;66:10658-10663.
23. Navarrete-Meneses M, Salas-Labadía C, Sanabrais-Jiménez
doi: 10.1158/0008-5472.CAN-06-1871 M, et al. Exposure to the insecticides permethrin and
malathion induces leukemia and lymphoma-associated
13. Perner D, Vierkötter A, Sugiri D, et al. Association between
sun-exposure, smoking behaviour and plasma antioxidant gene aberrations in vitro. Toxicol In Vitro. 2017;44:17-26.
levels with the different manifestation of skin ageing signs doi: 10.1016/j.tiv.2017.06.013

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