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Global Translational Medicine Open carpal tunnel release surgical outcomes

complications. In addition, McNemar’s test was used to ranged from 22 to 90 years, with a mean age of CTS
perform pair-wise comparisons of outcome measurements presentation at 47 years (SD = 12.1). Of the participants,
between the pre-operative and post-operative phases. The 204 (79.7%) were female, while 52 (20.3%) were male.
statistical significance level was set at P-value less than 5% The mean BMI was 28.08 m /kg (SD = 2.5), falling within
2
(P < 0.05). the “overweight” range according to the World Health
Organization classification.
2.3. Ethical consideration
The NCS results were assessed and classified according
The study adhered to ethical protocols in accordance with to the Bland classification, which is based on the
the Helsinki’s Declaration, 2013 revision. All patients electrophysiological severity of the condition. Following
were duly informed about the study and were assured of the NCS assessment, it was observed that 50.8% of the
the confidentiality of their data. Throughout the course
of this study, every precaution was taken to prevent any patients demonstrated severe compression of the median
harmor potential risks to the patients. Permission from nerve. During the pre-operative stage, clinical examinations
patients was obtained through both verbal communication revealed that 95.0% of the CTS patients reported
and the acquisition of written informed consent. No experiencing dull aching discomfort in their hand and
experimental intervention took place during or after the forearm, accompanied by hand paresthesia and numbness.
study. Furthermore, the study received full approval from In addition, clumsiness was observed in 66 patients (25.8%),
the Scientific Research and Ethics Committee at Zliten and thenar muscle atrophy was noted in 13 patients (5.0%).
Teaching Hospital in Libya. Out of 256 patients, 232 (90.6%) were highly satisfied
with the procedure and reported no recurrence of symptoms
3. Results during the follow-up period. Conversely, 24 patients (9.4%)

A total of 256 patients were included in this data analysis. experienced post-operative complications. Three main
Demographic information of study participants and complications were documented after OCTR during the
clinical presentation is shown in Table 1. Descriptive follow-up period. Five patients (2.0%) encountered wound
statistics reveal that 127 patients (49.6%) presented bilateral dehiscence (superficial infection), which was treated
CTS, 92 patients (35.9%) with right CTS, and 37 patients with dressings and antibiotics. Fifteen patients (5.9%)
(14.5%) with left CTS. The age of the study participants presented with recurrent CTS symptoms (three of them

Table 1. Demographic information and clinical presentation of patients

Variable/Clinical parameter Mean (SD) Frequency (n=256) Percentage
Age 47 years (12.1)
Gender
Male 5220.3
Female 204 79.7
BMI 28.08 m /kg (2.5)
2
CTS presentation
Bilateral CTS 12749.6
Right CTS 9235.9
Left CTS 37 14.5
Nerve conduction study assessment
Mild median nerve compression 41 16.0
Moderate median nerve compression 85 33.2
Severe median nerve compression 130 50.8
CTS presentation at preoperative stage
Dull aching discomfort in the hand and 24395.0
forearm with hand paresthesia and numbness
Clumsiness 6625.8
Thenar muscle atrophy 13 5.0
Abbreviation: CTS: Carpal tunnel syndrome.

Volume 2 Issue 4 (2023) 4 https://doi.org/10.36922/gtm.1019