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Global Translational Medicine





                                        ORIGINAL RESEARCH ARTICLE
                                        Surgical outcome of open carpal tunnel release:

                                        A 2-year case series study at Zliten Teaching
                                        Hospital, Libya



                                                                                        3
                                                      1,2
                                        Mohamed Gwila *, Mostafa Ebshina , Syeda Humayra , and
                                                                        2
                                        Moniruddin Chowdhury 3,4
                                        1 Department of Orthopaedics and Traumatology, Faculty of Medicine, Al Asmarya Islamic University,
                                        Zliten, Libya
                                        2 Department of Orthopaedics, Zliten Teaching Hospital, Zliten, Libya
                                        3 Department of Public Health, Faculty of Allied Health Sciences, Daffodil International University,
                                        Daffodil Smart City, Birulia, Dhaka, Bangladesh
                                        4 Department of Medicine, Faculty of Medicine, AIMST University, Bedong, Kedah, Malaysia




                                        Abstract

                                        Carpal tunnel syndrome (CTS) is the most commonly diagnosed peripheral
                                        neuropathy, with a prevalence of 1 – 16% within the general population. If left
                                        untreated, it can lead to permanent dysfunctionality and disability. This study
                                        aimed  to  determine  the  outcomes  and  complications  associated  with  open
                                        carpal tunnel release surgery (OCTR), compare the presentation of CTS symptoms
                                        before and after the operation, and investigate the factors contributing to post-
            *Corresponding author:      operative complications. To achieve these objectives, a case series design was
            Mohamed Gwila
            (ghwila001@gmail.com)       employed, and the study was conducted at the Department of Orthopedics
                                        and  Traumatology in Zliten  Teaching Hospital, Libya, from January 2016 to
            Citation: Gwila M, Ebshina M,
            Humayra S, et al., 2023, Surgical   December 2018. A total of 256 patients who had opted to undergo OCTR of the
            outcome of open carpal tunnel   transverse carpal ligament during the preoperative stage were enrolled and
            release: A 2-year case series study   prospectively followed  up for 2  years. The  post-operative follow-up  analysis
            at Zliten Teaching Hospital, Libya.
            Global Transl Med, 2(4): 1019.   revealed a statistically significant reduction in symptoms such as dull aching
            https://doi.org/10.36922/gtm.1019   discomfort in the hand and forearm, as well as paresthesia and numbness when
                                        compared to the pre-operative period (10.2% vs. 90.5%; P < 0.0001). However,
            Received: May 30, 2023
            Accepted: October 7, 2023   there were no significant differences in clumsiness (18.8% vs. 25.8%; P = 0.256)
            Published Online: November 6,   or thenar muscle atrophy (1.6% vs. 5.0%; P = 0.194). The majority of the patients
            2023                        (90.6%) expressed high levels of satisfaction with the procedure, reporting no
            Copyright: © 2023 Author(s).   recurrence of symptoms. In contrast, only 9.4% of patients experienced post-
            This is an Open-Access article   operative complications. The study findings revealed no significant correlation
            distributed under the terms of the
            Creative Commons Attribution   between post-operative complications and body mass index (P  = 0.194).
            License, permitting distribution,   Nonetheless, a statistically significant association was observed between the
            and reproduction in any medium,   severity of nerve conduction and post-operative complications (P  = 0.011).
            provided the original work is
            properly cited.             In summary, the open release of the transverse carpal ligament resulted in
                                        positive surgical outcomes.
            Publisher’s Note: AccScience
            Publishing remains neutral with
            regard to jurisdictional claims in
            published maps and institutional   Keywords: Carpal tunnel syndrome; Libya; Open release; Outcomes; Surgery
            affiliations.





            Volume 2 Issue 4 (2023)                         1                        https://doi.org/10.36922/gtm.1019
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