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Global Translational Medicine                                    Open carpal tunnel release surgical outcomes



            1. Introduction                                    method for reliably alleviating symptoms and performed
                                                               in current orthopedic practice involves the decompression
            Carpal tunnel syndrome (CTS) is defined by the     of  the  median  nerve  through  an  open  release  of  the
            American Academy of Orthopedic Surgeons (AAOS) as a   transverse carpal ligament . In cases where surgery
                                                                                     [10]
            “symptomatic compression neuropathy of the median nerve   is indicated, it is essential to consider the potential for
            at the level of the wrist” . This specific nerve entrapment   significant complications. The clinical symptoms that may
                               [1]
            neuropathy accounts for 90% of all neuropathies . CTS   ensue following these complications can be more severe
                                                    [2]
            stands as the most commonly diagnosed peripheral   and distressing than the patients’ original complaints .
                                                                                                         [1]
            neuropathy, exhibiting a prevalence of 1 – 16% in the general
            population , with a notable predominance in females .   Irrespective of the chosen surgical technique, carpal
                     [3]
                                                        [4]
            Clinically, CTS can be graded into mild, moderate, and   tunnel surgery generally yields favorable results. While
            severe forms based on the symptom’s history, presentation,   ECTR has been demonstrated to offer a quicker recovery
            and severity . Initial symptoms of CTS include discomfort   time  and  reduced  postoperative  discomfort  compared
                     [5]
                                                                                                           [11]
            or soreness, numbness, and paresthesia. These symptoms   to OCTR, it may still result in a number of problems .
            most frequently manifest in the thumb, index finger,   The standard OCTR, which involves a longitudinal skin
            middle  finger, and radial half (thumb  side) of the  ring   incision directly over the transverse carpal ligament, has
            finger, although some variation may occur. In addition,   consistently yielded favorable outcomes . However,
                                                                                                  [12]
            individuals with CTS may experience soreness in the   this technique has been associated with difficult-to-treat
            affected arm. As the condition worsens, hand weakness,   complications, including discomfort in the scar, pain in
            impaired fine motor coordination, clumsiness, and thenar   the thenar and hypothenar (pillar) muscles, and weakness
                                                                                         [11]
                                                                                                            [9]
            muscle atrophy may become apparent. Various factors,   in the pinch and grasp strength . A systematic review
            including fluid retention, particularly during pregnancy,   was conducted to compare OCTR  and ECTR  methods,
            can contribute to the development of CTS.  Patients often   assessing post-surgical outcomes and complications.
                                              [2]
            report a worsening of their symptoms during the night,   The study discovered that ECTR had a higher incidence
            causing sleep disturbances .                       of superficial palmar arch injuries and transient nerve
                                 [6]
                                                               damage between 1960 and 1990 .
                                                                                        [9]
              CTS is a frequently encountered condition resulting
            from  the  compression  of  the  median  nerve  within the   Lee and Strickland developed a limited-open technique
            carpal tunnel of the wrist. However, if left untreated, it can   employing specifically designed instruments known as the
            result in long-term dysfunction and physical impairment .   “Indian atome.” This approach features a smaller palmar
                                                        [6]
            Notably, the progression of symptoms in CTS is not always   incision, measuring just 1.5  cm in length, with the aim
            linear, and in some cases, it spontaneously resolves over   of minimizing the trauma caused by OCTR. The authors
            time. In these circumstances, CTS may naturally resolve   reported achieving results similar to those performed
            or respond to minimal self-care measures. In cases where   with  ECTR  while  experiencing  fewer  complications .
                                                                                                           [13]
            symptoms persist, conservative treatments and non-  This technique combines the simplicity of open release
            surgical interventions, such as wrist splints or steroid   with  reduced  surgical  trauma,  a  smaller  incision,  and
            injections, are frequently employed to manage mild-to-  decreased postoperative morbidity. The procedure has
            moderate symptoms. Surgical release (decompression) of   been found to be straightforward to implement, and
            the carpal tunnel becomes a consideration if non-surgical   numerous patients have reported excellent outcomes with
                                                                               [11]
            remedies fail to alleviate the symptoms associated with   fewer complications . Despite the advent of endoscopic
            CTS [2,7] .                                        release, the incidence of nerve injuries has not significantly
                                                               decreased, although there has been a gradual decline
              The individualized treatment modality is customized
            through a comprehensive assessment of several factors,   in issues brought on by vascular injuries. The increased
            including  the  severity  of  the  symptoms  of  the  limb,  the   rate of transient nerve injury and the accompanying
            psychosocial status of the patient, and the surgeon’s capacity   skin complications should be considered when deciding
                                                                                                      [9]
            to execute a well-outlined treatment plan with precision   between these two widely used surgical methods .
            and safety, all aimed at achieving a successful outcome .   Older age, female sex, and a high body mass index (BMI)
                                                        [8]
            In the management of CTS, a range of surgical procedures   have all been identified as risk factors for CTS, according to
            has been described, including endoscopic carpal tunnel   a review article . High BMI was substantially associated
                                                                           [14]
            release (ECTR) or open carpal tunnel release (OCTR).   with CTS, although not with the severity of the condition,
            These techniques can be further categorized as traditional   as confirmed by a cross-sectional analytical investigation
            open, limited open, single-portal endoscopic, and two-  that yielded comparable results . A  crucial step in
                                                                                          [15]
            portal endoscopic approaches . The preferred treatment   defining the prognostic and therapeutic measures involves
                                    [9]
            Volume 2 Issue 4 (2023)                         2                        https://doi.org/10.36922/gtm.1019
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