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Global Translational Medicine                                  Evidence-based approach for TCM development



              The  successful  modernization  of  TCM  clinical   Funding
            development has the potential to bring significant benefits
            to patients worldwide. By integrating TCM into modern   None.
            healthcare systems, patients may gain access to safe,   Conflict of interest
            effective, and holistic treatment options that complement
            and enhance the current standard of care. Moreover, the   The authors declare that they have no competing interests.
            modernization of TCM can contribute to the advancement   Author contributions
            of medical knowledge by fostering a deeper understanding
            of the mechanisms underlying the therapeutic effects of   Conceptualization: Shein-Chung Chow
            TCM treatments and by identifying new avenues for drug   Writing – original draft: Yinuo Zhang
            discovery and development.                         Writing – review & editing: All authors
              However, the modernization of TCM clinical       Ethics approval and consent to participate
            development is not without its challenges. It requires a
            collaborative effort among TCM practitioners, Western   Not applicable.
            clinicians, researchers, and regulatory authorities to   Consent for publication
            establish standardized diagnostic procedures, evaluation
            methods, and regulatory frameworks that are acceptable   Not applicable.
            to both TCM and Western medical communities. It also
            calls for a willingness to embrace innovative thinking and   Availability of data
            novel approaches to clinical trial design and analysis while   Not applicable.
            maintaining the highest standards of scientific rigor and
            ethical conduct.                                   References
              Looking ahead, the future of healthcare may increasingly   1.   Liu  S,  Matsuo  T,  Matsuo  C,  Abe  T.  Traditional  Chinese
            involve the synergy of these two systems. TCM’s plant-  medicines and prescriptions brought from China to Japan
            based formulations could provide alternative or adjunctive   by a Monk (Jianzhen, Japanese: Ganjin): A historical review.
            therapies to synthetic drugs, potentially reducing side   Compounds. 2022;2:267-284.
            effects and improving patient outcomes. For instance, the      doi: 10.3390/compounds2040022
            combination  of  TCM’s  multi-component  therapies  with   2.   International Classification of Diseases (ICD). Available
            the precision of WM could lead to more personalized and   from:  https://www.who.int/standards/classifications/
            effective treatments.                                 classification-of-diseases [Last accessed on 2024 Sep 18].
              However, achieving this integration will require   3.   Lam WC, Lyu A, Bian Z. ICD-11: Impact on traditional
            ongoing research, validation, and collaboration between   Chinese medicine and World Healthcare Systems.  Pharm
            TCM practitioners, scientists, and regulatory bodies. The   Med. 2019;33(5):373-377.
            goal should be to preserve the unique characteristics of      doi: 10.1007/s40290-019-00295-y
            TCM while ensuring that its practices meet the rigorous   4.   Xin Y, Dai YY, Zhang XW,  et al. A  brief discussion on
            safety and efficacy standards expected in modern medicine.   evidence-based  clinical  research  of  traditional  Chinese
            This approach not only holds promise for enhancing    medicine. Ann Palliat Med. 2021;10(12):12937-12944.
            patient care but also for expanding the therapeutic arsenal
            available to modern medicine.                         doi: 10.21037/apm-20-697
                                                               5.   He J, Hou XY. The potential contributions of traditional
              The  modernization  of  TCM  clinical  development   Chinese medicine to emergency medicine. World J Emerg
            represents a significant opportunity to harness the potential   Med. 2013;4(2):92-97.
            of this ancient healing tradition and to bring its benefits
            to patients in a safe, effective, and scientifically validated      doi: 10.5847/wjem.j.issn.1920-8642.2013.02.002
            manner.  By embracing the  challenges and  opportunities   6.   De Felipe ÍO. The universality of science and traditional
            associated with this process, we can work toward a future in   Chinese medicine: A philosophical survey. Sci Educ (Dordr).
            which TCM and WM are integrated seamlessly, providing   2021;30(6):1353-1370.
            patients with the best possible care and outcomes.     doi: 10.1007/s11191-021-00249-4

            Acknowledgments                                    7.   Zhao C, Liu Z, Lin J, Wang YP, Wang YP, Shang HC.
                                                                  Standardizing individualized efficacy  evaluation  to
            None.                                                 optimize evidence-using pattern in traditional Chinese


            Volume 3 Issue 3 (2024)                         9                               doi: 10.36922/gtm.4190
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