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Global Translational Medicine Graphene oxide in cancer drug delivery applications
high drug-loading capacity for a variety of drugs and older adults: Shifting away from problematic polypharmacy.
therapeutic molecules. A deep understanding of how Expert Opin Pharmacother. 2024;25:1199-1208.
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graphene interacts with living cells, especially the process doi: 10.1080/14656566.2024.2374048
of cellular absorption, is essential. This knowledge will
undoubtedly aid in the future advancement of graphene- 5. Jurj A, Braicu C, Pop LA, Tomuleasa C, Gherman C,
Berindan-Neagoe I. The new era of nanotechnology, an
based nanocarriers, particularly in cancer therapies, where alternative to change cancer treatment. Drug Des Devel Ther.
these materials have already demonstrated significant 2017;11:2871-2890.
promise. In conclusion, further studies on GO-/rGO-
83
based nanocomposites will provide valuable insights, 6. Shafiee A, Iravani S, Varma RS. Graphene and graphene
oxide with anticancer applications: Challenges and future
potentially paving the way for their broader clinical perspectives. MedComm (2020). 2022;3:e118.
application in the coming years.
doi: 10.1002/mco2.118
Acknowledgments 7. Fusco L, Gazzi A, Peng G, et al. Graphene and other 2D
The figure was created using Biorender.com. materials: A multidisciplinary analysis to uncover the
hidden potential as cancer theranostics. Theranostics.
Funding 2020;10:5435-5488.
None. doi: 10.7150/thno.40068
8. Pourmadadi M, Soleimani Dinani H, Saeidi Tabar F, et al.
Conflict of interest Properties and applications of graphene and its derivatives
The authors declare no conflicts of interest. in biosensors for cancer detection: A comprehensive review.
Biosensors (Basel). 2022;12:269.
Author contributions doi: 10.3390/bios12050269
Conceptualization: Subhadeep Das 9. Song S, Shen H, Wang Y, et al. Biomedical application
Writing – original draft: Subhadeep Das of graphene: From drug delivery, tumor therapy, to
Writing – review & editing: All authors theranostics. Colloids Surf B Biointerfaces. 2020;185:110596.
doi: 10.1016/j.colsurfb.2019.110596
Ethics approval and consent to participate
10. Jain VP, Chaudhary, S, Sharma D, et al. Advanced
Not applicable. functionalized nanographene oxide as a biomedical agent
for drug delivery and anti-cancerous therapy: A review. Eur
Consent for publication Polym J. 2021;142:110124.
Not applicable. doi: 10.1016/j.eurpolymj.2020.110124
Availability of data 11. Kadkhoda J, Tarighatnia A, Barar J, Aghanejad A, Davaran S.
Recent advances and trends in nanoparticles based
Not applicable. photothermal and photodynamic therapy. Photodiagnosis
Photodyn Ther. 2022;37:102697.
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Volume 3 Issue 3 (2024) 8 doi: 10.36922/gtm.4602

