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Global Translational Medicine                               Graphene oxide in cancer drug delivery applications



            high  drug-loading capacity  for a  variety of  drugs  and   older adults: Shifting away from problematic polypharmacy.
            therapeutic molecules.  A deep understanding of how   Expert Opin Pharmacother. 2024;25:1199-1208.
                              83
            graphene interacts with living cells, especially the process      doi: 10.1080/14656566.2024.2374048
            of cellular absorption, is essential. This knowledge will
            undoubtedly aid in the future advancement of graphene-  5.   Jurj A, Braicu C, Pop LA, Tomuleasa C, Gherman C,
                                                                  Berindan-Neagoe I. The new era of nanotechnology, an
            based nanocarriers, particularly in cancer therapies, where   alternative to change cancer treatment. Drug Des Devel Ther.
            these materials have already demonstrated significant   2017;11:2871-2890.
            promise.  In conclusion, further studies on GO-/rGO-
                   83
            based  nanocomposites  will  provide  valuable  insights,   6.   Shafiee A, Iravani S, Varma RS.  Graphene and  graphene
                                                                  oxide with anticancer applications: Challenges and future
            potentially  paving  the  way  for  their  broader  clinical   perspectives. MedComm (2020). 2022;3:e118.
            application in the coming years.
                                                                  doi: 10.1002/mco2.118
            Acknowledgments                                    7.   Fusco  L,  Gazzi  A, Peng  G,  et al.  Graphene  and  other 2D
            The figure was created using Biorender.com.           materials: A  multidisciplinary analysis to uncover the
                                                                  hidden  potential  as  cancer  theranostics.  Theranostics.
            Funding                                               2020;10:5435-5488.
            None.                                                 doi: 10.7150/thno.40068
                                                               8.   Pourmadadi M, Soleimani Dinani H, Saeidi Tabar F, et al.
            Conflict of interest                                  Properties and applications of graphene and its derivatives
            The authors declare no conflicts of interest.         in biosensors for cancer detection: A comprehensive review.
                                                                  Biosensors (Basel). 2022;12:269.
            Author contributions                                  doi: 10.3390/bios12050269
            Conceptualization: Subhadeep Das                   9.   Song S, Shen H, Wang Y,  et al. Biomedical application
            Writing – original draft: Subhadeep Das               of  graphene: From drug delivery, tumor therapy, to
            Writing – review & editing: All authors               theranostics. Colloids Surf B Biointerfaces. 2020;185:110596.
                                                                  doi: 10.1016/j.colsurfb.2019.110596
            Ethics approval and consent to participate
                                                               10.  Jain VP, Chaudhary, S, Sharma D,  et al. Advanced
            Not applicable.                                       functionalized nanographene oxide as a biomedical agent
                                                                  for drug delivery and anti-cancerous therapy: A review. Eur
            Consent for publication                               Polym J. 2021;142:110124.
            Not applicable.                                       doi: 10.1016/j.eurpolymj.2020.110124

            Availability of data                               11.  Kadkhoda J, Tarighatnia A, Barar J, Aghanejad A, Davaran S.
                                                                  Recent advances and trends in nanoparticles based
            Not applicable.                                       photothermal and photodynamic therapy.  Photodiagnosis
                                                                  Photodyn Ther. 2022;37:102697.
            References
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            Volume 3 Issue 3 (2024)                         8                               doi: 10.36922/gtm.4602
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