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Global Translational Medicine rh-PDGF for peri-intrabony defects

Table 1. Clinical parameters at baseline and 6 months after treatment
Cases Baseline PD 6 months Baseline 6 months post‑operative Baseline CAL 6 months
(M‑D) post‑operative GRD GRD M‑D post‑operative CAL
(PD M‑D) M‑D M‑D M‑D
Case 1 6/3/2 2/2/2 −1/−1/−1 −1/−1/−1 5/2/1 1/1/1
Case 2 3/2/7 3/3/3 −1/0/1 −1/0/2 2/2/8 2/3/5
Case 3 4/3/6 3/3/3 0/0/0 0/0/0 4/3/6 3/3/3
Case 4 4/3/6 3/2/3 −2/−2/−2 −1/−1/0 2/1/4 2/1/3
Case 5 2/3/8 2/2/5 3/3/3 3/3/4 5/6/11 5/5/9
Case 6 3/2/6 3/2/3 −2/−2/−2 −1/−1/−1 1/0/4 2/1/2
Case 7 2/2/6 2/1/1 −2/−2/−2 −1/−1/−1 0/0/4 1/0/0
Case 8 6/3/2 4/2/2 1/1/0 2/2/1 7/4/2 6/4/3
Case 9 5/2/2 3/2/2 −1/−1/−1 −1/−1/−1 4/1/1 2/1/1
Case 10 8/5/5 6/4/4 −2/−2/0 −2/−2/0 6/3/5 4/2/4
Case 11 4/3/7 3/3/4 −1/0/0 −1/0/−1 3/3/7 2/3/5
Case 12 6/3/3 3/2/2 −2/−2/−2 1/2/1 4/1/1 4/4/3
Case 13 5/5/7 3/3/4 1/1/1 4/5/5 6/6/8 7/8/9
Case 14 4/4/7 3/3/3 −2/−2/−2 −1/−1/−1 2/2/5 2/2/2
Abbreviations: CAL: Clinical attachment level; GRD: Gingival recession depth; M-D: Mesial to distal; PD: Probing depth.

the risk of gingival recession and leverages the regenerative Investigation: Thaer Alqadoumi
capacity of surrounding periodontal tissues. Methodology: Thaer Alqadoumi, Fatemeh Samavatijame
While the study offers valuable insights, it is limited by Writing-original draft: Fatemeh Samavatijame, Noor Daras
the small sample size and the lack of statistics. Additional Writing-review & editing: All authors
research is imperative to validate these results, explore Ethics approval and consent to participate
long-term stability, and assess the overall effectiveness of
the treatment. This study was conducted at a private practice with patients
who consented to the procedures. No ethical approval was
4. Conclusion required.
This report demonstrates the potential of a non-surgical Consent for publication
periodontal treatment using a rh-PDGF-BB-infused
collagen sponge to successfully regenerate periodontal tissue The participants provided verbal consent for the release of
in intrabony defects located in the anterior esthetic area. their data.
Further research is required to validate the result, assess long-
term stability, and evaluate the overall treatment efficacy. Availability of data
Data used in this work are available from the corresponding
Acknowledgments author upon reasonable request.
None.
References
Funding 1. Anoixiadou S, Parashis A, Vouros I. Minimally invasive non-

None. surgical technique in the treatment of intrabony defects-a
narrative review. Dent J (Basel). 2023;11(1):25.
Conflict of interest doi: 10.3390/dj11010025

The authors declare no conflict of interest. 2. Nibali L, Koidou V, Salomone S, et al. Minimally invasive
non-surgical vs. Surgical approach for periodontal
Author contributions intrabony defects: A randomised controlled trial. Trials.

Conceptualization: Thaer Alqadoumi, Muhammad H. A. 2019;20(1):461.
Saleh doi: 10.1186/s13063-019-3544-8

Volume 3 Issue 3 (2024) 4 doi: 10.36922/gtm.3313