Page 20 - GTM-3-4

Global Translational Medicine Parkinson’s: From cause to cure

51. Cui Z, Wei H, Goding C, Cui R. Stem cell heterogeneity, and implications for clinical practice. Genes (Basel).
plasticity, and regulation. Life Sci. 2023;334:122240. 2021;12(7):1006.
doi: 10.1016/j.lfs.2023.122240 doi: 10.3390/genes12071006
52. Boika A, Aleinikava N, Chyzhyk V, Zafranskaya M, 59. Kang L, Jin S, Wang J, et al. AAV vectors applied to the
Nizheharodava D, Ponomarev V. Mesenchymal stem cells in treatment of CNS disorders: Clinical status and challenges.
Parkinson’s disease: Motor and nonmotor symptoms in the J Control Release. 2023;355:458-473.
early posttransplant period. Surg Neurol Int. 2020;11:380.
doi: 10.1016/J.JCONREL.2023.01.067
doi: 10.25259/SNI_233_2020
60. Grote J, Patel N, Bates C, Parmar MS. From lab bench to hope:
53. Park JM, Rahmati M, Lee SC, Shin JI, Kim YW. Effects of A review of gene therapies in clinical trials for Parkinson’s
mesenchymal stem cell on dopaminergic neurons, motor disease and challenges. Neurol Sci. 2024;45:4699-4710.
and memory functions in animal models of Parkinson’s
disease: A systematic review and meta-analysis. Neural doi: 10.1007/S10072-024-07599-1
Regen Res. 2024;19(7):1584-1592. 61. Chen Y, Hong Z, Wang J, et al. Circuit-specific gene therapy
doi: 10.4103/1673-5374.387976 reverses core symptoms in a primate Parkinson’s disease
model. Cell. 2023;186(24):5394-5410.e18.
54. Park S, Park CW, Eom JH, et al. Preclinical and dose-ranging
assessment of hESC-derived dopaminergic progenitors doi: 10.1016/J.CELL.2023.10.004
for a clinical trial on Parkinson’s disease. Cell Stem Cell. 62. Fan JQ, Lu WJ, Tan WQ, et al. Effectiveness of
2024;31(1):25-38.e8. acupuncture for anxiety among patients with parkinson
doi: 10.1016/J.STEM.2023.11.009 disease: A randomized clinical trial. JAMA Netw Open.
2022;5(9):e2232133.
55. Jiang S, Wang H, Yang C, et al. Phase 1 study of safety and
preliminary efficacy of intranasal transplantation of human doi: 10.1001/jamanetworkopen.2022.32133
neural stem cells (ANGE-S00 ) in Parkinson’s disease. 63. Yan M, Fan J, Liu X, et al. Acupuncture and sleep quality
3
J Neurol Neurosurg Psychiatry. 2024;95:1102-1111. among patients with Parkinson disease: A randomized
doi: 10.1136/JNNP-2023-332921 clinical trial. JAMA Netw Open. 2024;7(6):e2417862.
56. Zheng X, Han D, Liu W, et al. Human iPSC-derived midbrain doi: 10.1001/jamanetworkopen.2024.17862
organoids functionally integrate into striatum circuits and 64. Jang JH, Park S, An J, et al. Gait disturbance improvement
restore motor function in a mouse model of Parkinson’s and cerebral cortex rearrangement by acupuncture in
disease. Theranostics. 2023;13(8):2673-2692. Parkinson’s disease: A pilot assessor-blinded, randomized,
doi: 10.7150/THNO.80271 controlled, parallel-group trial. Neurorehabil Neural Repair.
2020;34(12):1111-1123.
57. Nalls MA, Blauwendraat C, Vallerga CL, et al. Identification
of novel risk loci, causal insights, and heritable risk for doi: 10.1177/1545968320969942
Parkinson’s disease: A meta-analysis of genome-wide 65. Oh JY, Lee H, Jang SY, et al. Central role of hypothalamic
association studies. Lancet Neurol. 2019;18(12):1091-1102.
circuits for acupuncture’s anti-parkinsonian effects. Adv Sci
doi: 10.1016/S1474-4422(19)30320-5 (Weinh). 2024;11:e2403245.
58. Day JO, Mullin S. The genetics of parkinson’s disease doi: 10.1002/ADVS.202403245

Volume 3 Issue 4 (2024) 12 doi: 10.36922/gtm.5082