Page 111 - GTM-4-1

Global Translational Medicine Comparative study of Schisandra species on VCI

vascular cognitive impairment. Trad Med Res. 2024;9:57. Stroke Res. 2015;6(1):69-77.
28. Fu Z, Wang X, Fan Y, et al. Brozopine ameliorates cognitive doi: 10.1007/s12975-014-0374-6
impairment via upregulating Nrf2, antioxidation and anti-
inflammation activities. Front Pharmacol. 2024;15:1428455. 36. Hattori Y, Enmi JI, Iguchi S, et al. Substantial reduction
of parenchymal cerebral blood flow in mice with bilateral
doi: 10.3389/fphar.2024.1428455 common carotid artery stenosis. Sci Rep. 2016;6(1):32179.
29. Cai H, Cai T, Zheng H, et al. The neuroprotective effects doi: 10.1038/srep32179
of danggui-shaoyao san on vascular cognitive impairment:
Involvement of the role of the low-density lipoprotein 37. Wang JY, Zhang GL, Yang YF, et al. Schisandra chinensis
receptor-related protein. Rejuvenation Res. 2020;23:420-433. Lignans exert antidepressant effects by promoting BV2
microglia polarization toward the M2 phenotype through
doi: 10.1089/rej.2019.2182 the activation of the cannabinoid receptor type-2-signal
30. Zheng V, Wong G. Neuroinflammation responses after transducer and activator of transcription 6 pathway. J Agric
subarachnoid hemorrhage: A review. J Clin Neurosci. Food Chem. 2022;70(44):14157-14169.
2017;42:7-11 doi: 10.1021/acs.jafc.2c04565
doi: 10.1016/j.jocn.2017.02.001 38. Song FJ, Zeng KW, Liao LX, Yu Q, Tu PF, Wang XM.
31. Kim T, Vemuganti R. Mechanisms of Parkinson’s disease- Schizandrin A inhibits microglia-mediated
related proteins in mediating secondary brain damage neuroninflammation through inhibiting TRAF6-NF-κB
after cerebral ischemia. J Cereb Blood Flow Metab. and JAK2-STAT3 signaling pathways. PLoS One.
2017;37(6):1910-1926. 2016;11(2):e0149991.
doi: 10.1177/0271678x17694186 doi: 10.1371/journal.pone.0149991
32. Ziemka-Nalecz M, Jaworska J, Zalewska T. Insights into 39. Zeng KW, Zhang T, Fu H, Liu GX, Wang XM. Schisandrin B
the neuroinflammatory responses after neonatal hypoxia- exerts anti-neuroinflammatory activity by inhibiting
ischemia. J Neuropathol Exp Neurol. 2017;76(8):644-654. the toll-like receptor 4-dependent MyD88/IKK/NF-κB
doi: 10.1093/jnen/nlx046 signaling pathway in lipopolysaccharide-induced microglia.
Eur J Pharmacol. 2012;692(1-3):29-37.
33. Xiao ZH, Xiao W, Li GL. Research progress on the
pharmacological action of Schisantherin A. Evid Based doi: 10.1016/j.ejphar.2012.05.030
Complement Alternat Med. 2022;2022:6420865. 40. Chen S, Ding YH, Shi SS, Tu XK. Schisandrin B inhibits
doi: 10.1155/2022/6420865 NLRP3 inflammasome pathway and attenuates early brain
injury in rats of subarachnoid hemorrhage. Chin J Integr
34. Jung CH, Hong MH, Kim JH, et al. Protective effect of a Med. 2022;28(7):594-602.
Phenolie-rich fraction from Schisandra chinensis against
H O -induced apoptosis in SH-SY5Y cells. J Pharmacy doi: 10.1007/s11655-021-3348-z
2
2
Pharmacol. 2007;59(3):455-462. 41. Qun E, Tang M, Zhang X, et al. Protection of seven
doi: 10.1211/jpp.59.3.0016 dibenzocyclooctadiene lignans from schisandra chinensis
against serum and glucose deprivation injury in SH-SY5Y
35. Khan MB, Hoda MN, Vaibhav K, et al. Remote ischemic
postconditioning: Harnessing endogenous protection in cells. Cell Biol Int. 2015;39(12):1418-1424.
a murine model of vascular cognitive impairment. Transl doi: 10.1002/cbin.10537

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