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Global Translational Medicine AA amyloidosis in rheumatoid arthritis

Cl+/Cl- – – Cl+ – – Cl+ – – – – Cl+ Cl+ Cl+ – – Cl+ – – – – – Cl+ Cl+ – – – – – (Cont'd...)

Cause of death rAAa-U cAAa rAAa-U cAAa rAAa-U rAAa-U cAAa – – – rAAa-U rAAa-U rAAa-U cAAa cAAa rAAa-U rAAa-U – – rAAa-U rAAa-U rAAa-U rAAa-U – cAAa rAAa-U rAAa-U –

Table 5. Mortality of systemic amyloid A amyloidosis (n=34), gastrointestinal amyloid A amyloidosis (n=31), and their amyloid A deposits per patient

Avg giAAa 0.09 0.09 0.45 0.35 0.39 0.52 0.27 NA NA 0.61 1.08 0.52 0.15 1.18 0.41 0.85 0.85 0.00 0.70 0.64 0.76 0.45 1.64 1.16 1.06 NA 0.68 1.34

Avg sAAa 1.097 0.437 0.788 0.905 0.593 0.963 0.351 0.432 0.278 0.10 0.393 1.834 0.856 0.338 0.426 1.271 1.023 0.524 0.252 0.943 0.448 1.666 0.915 0.022 0.074 1.025 0.569 0.106

Accompanying disease Atherosclerosis – – DM-atherosclerosis Atherosclerosis – Tuberculosis-Fc-mTb – Atherosclerosis – Atherosclerosis Neurinoma pararenal-JCA Pancreas CA Gall-bladder CA – DM7 DM-hypertension DM-atherosclerosis Alveolar CA-atherosclerosis – Neurinoma n. VIII.-atherosclerosis – – RA-atherosclerosis-HT – – – Tuberculosis-Fc-mTb

Cause of death Myocardial necrosis Multifocal myocardiocytolysis Myocardial necrosis-CI Bronchopneumonia Multifocal myocardiocytolysis

Uremia Circulatory failure Uremia Uremia Uremia Peritonitis- sepsis Sepsis Peritonitis Uremia Uremia Uremia Circulatory failure Circulatory failure Uremia Uremia Uremia Uremia Uremia Uremia Pulmonary emboli Circulatory failure Uremia Uremia

Complication 2 – – – – – – sAAa sAAa – sAAa – – – – – – AV AV mTu-sporadic vasculitis a – – – – sAAa AV – Femoral artery & vein thrombosis sAAa

Complication 1 sAAa sAAa sAAa sAAa sAAa sAAa AV Perforation sAAa Perforation sAAa sAAa sAAa sAAa sAAa sAAa sAAa sAAa sAAa sAAa sAAa sAAa sAAa Vertebral fracture sAAa sAAa sAAa AV

Basic disease RA-gastric ulcer RA-duodenal ulcer

RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA RA Ependymoma RA RA RA RA
f/m f f m f f f f f f f f m f f f f m f f f m m f f f f f f
Pr. n 0] /y 237/70 45/74 232/74 367/75 39/76 137/76 395/76 162/78 266/78 76/79 80/80 181/80 265/80 430/80 322/81 255/83 43/85 90/85 226/85 V/T 342/86 53/87 73/87 155/87 243/87 174/88 203/88 240/88

Total 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28

Volume 4 Issue 1 (2025) 119 doi: 10.36922/gtm.5325