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International

                                                                         Journal of Bioprinting



                                        RESEARCH ARTICLE
                                        Parametric design and performance study of

                                        continuous gradient triply periodic minimal
                                        surface bone scaffold



                                        Shuangyu Liu , Jinlong Feng , Fulong Zhang *, Weibo Jiang ,
                                                    1
                                                                              1
                                                                                           2
                                                                1
                                        Tatiana Mikhailovna Vasilieva , Ping Lu , and Sen Lu 1
                                                                 3
                                                                         4
                                        1 College of Mechanical Engineering, Yancheng Institute of Technology, Yancheng, Jiangsu, China
                                        2 Department of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin, China
                                        3 Joint Institute for High Temperatures of Russian Academy of Sciences, Izhorskaya str., 13, Bd.2,
                                        Moscow, Russia
                                        4 College of Automotive Engineering, Yancheng Institute of Technology, Yancheng, Jiangsu, China


                                        Abstract

                                        Continuous gradient triply periodic minimal surface (TPMS) porous structure has
                                        been proven to be one of the most suitable structures for bone implants due to
                                        their excellent mechanical properties and high porosity.  This study establishes
                                        a parametric modeling method for continuous gradient  TPMS structures and
                                        optimizes the TPMS porous structure with a continuous gradient change in porosity.
                                        Ti-6Al-4V continuous gradient TPMS porous structures were prepared using powder
                                        bed fusion (PBF). The mechanical properties and permeability of the continuous
                                        gradient TPMS porous structure were studied. The results indicate that the porosity
                                        control parameter C for gradient continuous change follows a linear function, with
            *Corresponding author:      the porosity increasing linearly within the specified range of values. The influence of
            Fulong Zhang                the periodic parameter ω on the mechanical properties and permeability of different
            (zhangfulong@ycit.edu.cn)
                                        types of TPMS structures varies. The Gyroid continuous gradient structure aligns
            Citation: Liu S, Feng J, Zhang F,    more closely with the mechanical properties and permeability of bone scaffolds.
            et al. Parametric design and
            performance study of continuous   Furthermore, a TPMS continuous gradient porous structure that is more suitable for
            gradient triply periodic minimal   trabecular bone implants was obtained through topology optimization design. A
            surface bone scaffold. Int J Bioprint.   bone implant model and object suitable for human trabecular bone were designed
            2024;10(2):2306.
            doi: 10.36922/ijb.2306      and printed, providing technical support for subsequent performance testing and
                                        application research of bone implants.
            Received: November 24, 2023
            Accepted: January 19, 2024
            Published Online: February 7, 2024
                                        Keywords: Triply periodic minimal surface; Additive manufacturing; Bone scaffold;
            Copyright: © 2024 Author(s).   Mechanical properties and permeability
            This is an Open Access article
            distributed under the terms of the
            Creative Commons Attribution
            License, permitting distribution,
            and reproduction in any medium,   1. Introduction
            provided the original work is
            properly cited.             Bone, the hardest tissue in the human body, serves multiple essential functions, including
            Publisher’s Note: AccScience   body support, movement facilitation, hematopoiesis, and effective promotion of blood
            Publishing remains neutral with   circulation. Extensive bone injuries are typically caused by trauma, osteomyelitis, or
            regard to jurisdictional claims in
            published maps and institutional   tumors. Medical studies have indicated that bone tissue loses its inherent capacity for
                                                                                     1
            affiliations.               repair when the size of the bone defect exceeds 30 mm.  Consequently, interventional


            Volume 10 Issue 2 (2024)                       312                                doi: 10.36922/ijb.2306
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