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International Journal of Bioprinting                          Bottom-up and top-down VAT photopolimerization




            soft tissue bioprinting. The unique characteristic of our   References
            dual bottom-up and top-down bioprinter can significantly
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            Acknowledgments                                       on-a-chip platforms for drug discovery and development.
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            A.K.M. acknowledges the NJIT start-up fund and the
            National Institutes of Health (NIH, R21DC018818).. D.N.   6.   Ho CT, Lin RZ, Chen RJ, et al. Liver-cell patterning lab chip:
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            acknowledges the Dutch Province of Limburg and the    vitro model of the blood-brain barrier (μBBB).  Lab Chip.
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            EAPA_384/2016 Atlantic KET Med Project is co-financed   9.   Huh D, Matthews BD, Mammoto A,  et al. Reconstituting
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            by the Interreg Atlantic Area Programme through the   2010;328(5986):1662-1668.
            European Regional Development Fund.
                                                               10.  Beckwitt CH, Clark AM, Wheeler S, et al. Liver ‘organ on a
            Conflict of interest                                  chip’. Exp Cell Res. 2018;63(1):15-25.
                                                               11.  Kim HJ, Huh D, Hamilton G, Ingber DE. Human gut-on-a-
            The authors declare no conflicts of interest.         chip  inhabited  by  microbial  flora  that  experiences  intestinal
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            Author contributions
                                                               12.  Wilmer MJ, Ng CP, Lanz HL,  Vulto P, Suter-Dick L,
            Conceptualization: Daniel Nieto                       Masereeuw R. Kidney-on-a-chip technology for drug-
            Investigation: Daniel Nieto                           induced nephrotoxicity screening.  Trends Biotechnol.
            Methodology: Daniel Nieto, Alberto Jorge de Mora      2016;34(2):156-170.
            Writing – original draft: Daniel Nieto, Anant Bhusal, Maria   13.  Phan DT, Bender RHF, Andrejecsk JW, et al. Blood–brain
               Kalogeropoulou                                     barrier-on-a-chip: Microphysiological systems that capture
            Writing – review & editing: Daniel Nieto, Amir K. Miri,   the complexity of the blood–central nervous system
               Lorenzo Moroni                                     interface. Exp Biol Med. 2017;242(17):1669-1678.
            Funding Acquisition: Daniel Nieto, Lorenzo Moroni  14.  Huebsch N, Loskill P, Deveshwar N, et al. Miniaturized iPS-
                                                                  cell-derived cardiac muscles for physiologically relevant
            Consent for publication                               drug response analyses. Sci Rep. 2016;(6):1-12.

            Not applicable.                                    15.  Mandrycky C, Wang Z, Kim K, Kim D-H. 3D bioprinting
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                                                                  422-434.
            Availability of data
                                                               16.  Arrigoni C, Lopa S, Candrian C, Moretti M. Organs-on-a-
            Raw data used in this work are available from the     chip as model systems for multifactorial musculoskeletal
            corresponding author upon reasonable request.         diseases. Curr Opin Biotechnol. 2020;63:79-88.



            Volume 10 Issue 2 (2023)                       541                                doi: 10.36922/ijb.1017
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