Page 346 - IJB-10-3

International Journal of Bioprinting Acoustic analysis of 3D-printed ossicles

Figure 14. ESP curves of HTH, H3H, and HHH.

normal ear ossicular model, with the malleus made of TC4, Acknowledgments
the incus made of TC4, and the stapes made of HA/PCL.
None.
Considering the different combinations of ossicular
chain materials, only a few combinations meet the hearing Funding
requirements, while most of the combinations do not yield
satisfactory results. However, from the perspective of finite This work was financially supported by the National
element analysis, these combinations provide preoperative Natural Science Foundation of China (52275224,
predictions for the reconstruction of the entire ossicular 52275296), the Fundamental Research Funds for the
chain. In future research, considering the difficulty in Central Universities (2020ZDPYMS22), and the Priority
obtaining temporal bone specimens, the focus can be Academic Program Development of Jiangsu Higher
shifted to developing external auxiliary detection devices Education Institutions (PAPD).
for the middle ear ossicular chain. Resonance phenomena
in numerical simulations can be addressed to improve Conflict of interest
the accuracy of measurement results. In vitro simulations The authors declare no conflicts of interest.
of various middle ear pathological environments can be
conducted to provide theoretical predictions for actual Author contributions
ossicular surgery. Finite element models of auditory
ossicles can be used to predict the effects of different Conceptualization: Jingbin Hao, Yin Zhu
materials, allowing for the rational selection and matching Funding acquisition: Jingbin Hao, Houguang Liu
of ideal materials for each ossicular position. Additionally, Investigation: Yin Zhu
the material properties of each part of the ossicles and Methodology: Jingbin Hao
their various positions can be studied in detail to ensure Supervision: Jingbin Hao, Houguang Liu
closer alignment with autologous ossicles’ biocompatibility Writing – original draft: Jingbin Hao, Yin Zhu,
requirements. Optimization of the entire ossicular chain’s Ding Shen
material combination, as well as the connection and Writing – review & editing: Md Thowfiqure Rahman,
structure of each part, should also be considered. Yinxin Kou

Volume 10 Issue 3 (2024) 338 doi: 10.36922/ijb.2040