Page 624 - IJB-10-3

International Journal of Bioprinting Wireless module system applied on 3D-printed implant

battery volume/overall weight reduction, and battery Methodology: Hsiao-Kuan Wu, Pei-Jung Tsai
capability enhancement to allow for battery installation on Writing – original draft: Cheng-Hsien Wu, Chun-Li Lin
the patient-specific implant for biomechanics detection. Writing – review & editing: Cheng-Hsien Wu, Chun-Li Lin
Besides, the WMS should also be compliant with U.S.
Food and Drug Administration (FDA) pre-clinical testing Ethics approval and consent to participate
requirements, such as meeting IEC60601 electrical safety Not applicable.
standards to mitigate risks. Furthermore, the patient-
specific implant may need to be designed with enough Consent for publication
internal space to accommodate the WMS and should
align with the surgical procedures of clinical physicians. Not applicable.
It should be highlighted that conducting biomechanical
in vitro fatigue tests with sole emphasis on single-point Availability of data
axial load forces is a limitation of this study for not able Data are available from the corresponding author upon
to explore the effects of other axial load forces. Following reasonable request.
the successful application of the wireless module, future
tests should expand their design to simulate more complex References
clinical occlusal scenarios. Moreover, it is essential to
conduct tests on implants in other mandibular areas to 1. Lim HK, Choi YJ, Choi WC, Song IS, Lee UL. Reconstruction
provide a comprehensive assessment. of maxillofacial bone defects using patient-specific long-
lasting titanium implants. Sci Rep. 2022;12:7538.
5. Conclusion doi: 10.1038/s41598-022-11200-0

This study developed a miniature wireless module for 2. Cheng KJ, Liu YF, Wang R, et al. Topological optimization
strain measurement, capable of transmitting strain signals of 3D printed bone analog with PEKK for surgical
through a Bluetooth-enabled APP system. The relationships mandibular reconstruction. J Mech Behav Biomed Mater.
2020;107:103758.
between strain, voltage, and force were determined, and doi: 10.1016/j.jmbbm.2020.103758
the accuracy of our WMS was verified using cantilever
beam model for the WMS. Biomechanical in vitro fatigue 3. Jung HW, Lee BS, Kwon YD, et al. Retrospective clinical
tests suggest that the developed wireless module’s strain study of mandible fractures. J Korean Assoc Oral Maxillofac
measurement system could potentially be utilized in a Surg. 2014;40(1):21-26.
doi: 10.5125/jkaoms.2014.40.1.21
mandibular 3D-printed patient-specific implant to predict
its biomechanical behavior in the future. Current fatigue 4. Maurer P, Eckert AW, Kriwalsky MS, Schubert J. Scope and
experimental results revealed that applying single-point limitations of methods of mandibular reconstruction: a long-
axial load force on the premolar led to fewer fatigue cycles term follow-up. Br J Oral Maxillofac Surg. 2010;48(2):100-
and an increased susceptibility of the implant to failure due 104.
doi: 10.1016/j.bjoms.2009.07.005
to the higher bending moment.
5. Lee SW, Kim HG, Ham MJ, Hong DGK, Kim SG, Rotaru H.
Acknowledgments Custom implant for reconstruction of mandibular continuity
defect. J Oral Maxillofac Surg. 2018;76:1370-1376.
None. doi: 10.1016/j.joms.2017.12.003

Funding 6. Patel A, Harrison P, Cheng A, Bray B, Bell RB. Fibular
reconstruction of the maxilla and mandible with immediate
This study was supported in part by NSTC project implant-supported prosthetic rehabilitation: jaw in a day.
112-2221-E-A49-009-MY3 and 111-2327-B-A49-006, Taiwan. Oral Maxillofac Surg Clin North Am. 2019;31:369-986.
doi: 10.1016/j.coms.2019.03.002
Conflict of interest 7. Toure G, Gouet E. Use of a 3-dimensional custom-
made porous titanium prosthesis for mandibular body
The authors declare no conflicts of interest.
reconstruction with prosthetic dental rehabilitation and
lipofilling. J Oral Maxillofac Surg. 2019;77:1305-1313.
Author contributions doi: 10.1016/j.joms.2018.12.026
Conceptualization: Cheng-Hsien Wu, Chun-Li Lin 8. Zhang L, Liu Z, Li B, et al. Evaluation of computer-assisted
Formal analysis: Hsiao-Kuan Wu, Pei-Jung Tsai mandibular reconstruction with vascularized fibular flap
Investigation: Cheng-Hsien Wu, Hsiao-Kuan Wu, Pei-Jung compared to conventional surgery. Oral Surg Oral Med Oral
Tsai, Chun-Li Lin Pathol Oral Radiol. 2016;121(2):139-148.

Volume 10 Issue 3 (2024) 616 doi: 10.36922/ijb.2553