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The arrival of commercial bioprinters – Towards 3D bioprinting revolution!

           table 2. Summary table of commercially available bioprinters
           (* IPF: Individually Pore Filling; IF: Injection Filling; FDM: Fused Deposition Modelling; NA: Not available; *: Information unavailable,
           #  Unless additional materials are highlighted, all extrusion-based bioprinters are at least capable of printing hydrogels)


                                  technology and   Nozzle  Build volume  Resolution (μm)  Number of  temperature
           company    Model              #          Diameter                         printing heads  control
                                  Materials        (μm)   (mm)        X/Y     Z      available
           3Dynamic   Alpha       Extrusion        *      150 × 150 × 60   ±75       1           *
           Systems                                                    (Accuracy)
                      Omega                               210 × 140 × 60   ±50       2           *
                                                                      (Accuracy)
           Advanced Life BioAssemblyBot  Extrusion  *     250 × 300 × 250  *         8           Tool: 5–110 °C
           Sciences                                                                  Interchangeable Bed: 5–110 °C
                                                                                     tools
                      Biobot                       *      190 × 100   10      10     5           NA
                                                          (Cylinder)  (Linear)  (Rotary)
                                                                      Rotational stage
           Aether     Aether 1    Extrusion, Droplet   50  315 × 229 × 132  1.055  0.00043 10+   Anodized aluminum
                                  jetting, FDM                                       Pneumatic: 8  heated syringe
                                                                                     FDM: 2      mount and stage
           Allevi     Allevi 1    Extrusion (hydrogel and  150  90 × 130 × 60  10  10  1         Nozzle: 4–200 °C
                                  thermopolymer)                                                 Bed: NA
                      Allevi 2    Extrusion        150    90 × 90 × 90  5.5   5     2            Nozzle: RT–160  °C
                                                                                                 Bed: NA
                      Allevi 6    Extrusion        *      *           1       1     6            Nozzle: 4–200 °C
                                  Thermoplastics,                                                Bed: RT–120 °C
                                  hydrogels
           Bio3D      Explorer    Extrusion        *      *           5       5     Up to 4      *
           Technologies
           CELLINK    INKREDIBLE+  Extrusion       100    130 × 80 × 100  10  10    2            Nozzle: Heating
                                                                                                 Bed: NA
                      BIO X       Extrusion, Inkjet, FDM  *  130 × 90 × 70  1  1    3            Nozzle: 4–130 °C
                                                                                    Heated       Bed: 4–60 °C
                                                                                     pneumatic: 2
                                                                                    Piston-driven: 1
           Cyfuse     Regenova    Kenzan method    170    10 × 20 × 18   –          Up to 2 types of NA
           biomedical                              (Needle)  (9 × 9)                spheroids
                                                          20 × 30 × 18
                                                          (26 × 26)
           Envision TEC Bioplotter                                    1       1     2            Nozzle: 30–250 °C
                      Starter                      100    150 × 150 × 140           Only high    Bed: NA
                                                                                    temperature
                                  Extrusion
                      Bioplotter  Hydrogel, thermoplastic,  100  150 × 150 × 140  1  1  3        Nozzle: 0–250 °C
                      Developer                                                     High and low  Bed: Available
                                  ceramic, metal paste
                      Bioplotter                   100    150 × 150 × 140  1  1     5            Nozzle: 0 – 250°C
                      Manufacturer                                                  High and low  Bed: -10 – 80°C
           GeSiM      BioScaffolder 3.1 Extrusion, Inkjet, Melt   *  310 × 200  2  10  3         Nozzle: * – 120°C
                                  electrospinning         (Area)                                 Bed: NA
           nScrypt    3Dn 300 TE   Extrusion       *      300 × 300 × 150  0.01  0.5  4          *
                      series
                                                                      ±5 (Accuracy)
           Pensees    VitarixTM   Extrusion        200    100 × 60    ±10           2           NA
                                                          (Area)      (Accuracy)
           REGEMAT 3D V1          IPF, IF, FDM *   100    150 × 150 × 110  150  0.4  FDM: 2     *
                                                                                    IPF/IF: up to 8






           12                          International Journal of Bioprinting (2018)–Volume 4, Issue 2
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