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International Journal of Bioprinting                                     Biomimetic osteochondral scaffold




            an innovative strategy for constructing 3D biomimetic-  experimental models. Biology. 2020;9(8):194.
            engineered osteochondral tissue with great potential for      doi: 10.3390/biology9080194
            osteochondral regeneration.                        3.   Abramoff B, Caldera FE. Osteoarthritis pathology,
                                                                  diagnosis, and treatment options.  Méd Clin North Am.
            Acknowledgments                                       2020;104(2):293-311.
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                                                               4.   Hermann  W,  Lambova  S,  Muller-Ladner  U.  Current
            Funding                                               treatment options  for  osteoarthritis.  Curr Rheumatol Rev.
                                                                  2017;14(2):108-116.
            This work was supported by the National Key R&D Program      doi: 10.2174/1573397113666170829155149
            of China (2022YFB4600600), the National Natural Science   5.   Madry H. Surgical therapy in osteoarthritis.  Osteoarthr
            Foundation of China (32271181 and 82300018), the      Cartil. 2022;30(8):1019-1034.
            Guangdong Basic and Applied Basic Research Foundation      doi: 10.1016/j.joca.2022.01.012
            (2021A1515111074), the Department of Education of   6.   Wei W, Dai H. Articular cartilage and osteochondral tissue
            Guangdong Province, China (2021ZDZX2014), the         engineering techniques: recent advances and challenges.
            Dongguan Science and Technology of Social Development   Bioact Mater. 2021;6(12):4830-4855.
            Program, Guangdong, China (20211800904542).           doi: 10.1016/j.bioactmat.2021.05.011
            Conflict of interest                               7.   Zhou L, Gjvm VO, Malda J, et al. Innovative tissue‐
                                                                  engineered  strategies  for  osteochondral  defect  repair  and
            The authors declare no conflicts of interest.         regeneration: current progress and challenges. Adv Healthc
                                                                  Mater. 2020;9(23):e2001008.
            Author contributions                                  doi: 10.1002/adhm.202001008
            Conceptualization:   Yaobin  Wu,  Chong  Wang,     8.   Colella F, Garcia JP, Sorbona M, et al. Drug delivery in
               Wenhua Huang,                                      intervertebral disc degeneration and osteoarthritis: selecting
                                                                  the optimal platform for the delivery of disease-modifying
            Formal analysis: Zhuosheng Lin, Ziyue Li, Zi Yan      agents. J Control Release. 2020;328:985-999.
            Investigation: Weiwei Su, Shiyu Li, Panjing Yin       doi: 10.1016/j.jconrel.2020.08.041
            Methodology: Weihan Zheng, Ling Wang
            Writing – original draft: Weiwei Su                9.   Rahimi  M, Charmi  G, Matyjaszewski K, Banquy X,
                                                                  Pietrasik J. Recent developments  in natural and synthetic
            Writing – review & editing:  Shiyu Li, Chong Wang,    polymeric drug delivery systems used for the treatment of
               Wenhua Huang                                       osteoarthritis. Acta Biomater. 2021;123:31-50.
                                                                  doi: 10.1016/j.actbio.2021.01.003
            Ethics approval and consent to participate
                                                               10.  Zhan A, Chen L, Sun W, et al. Enhancement of diabetic
            Not applicable.                                       wound healing using a core-shell nanofiber platform with
                                                                  sequential antibacterial, angiogenic, and collagen deposition
            Consent for publication                               activities. Mater Des. 2022;218:110660.
                                                                  doi: 10.1016/j.matdes.2022.110660
            Not applicable.
                                                               11.  He W, Li C, Zhao S, et al. Integrating coaxial electrospinning
            Availability of data                                  and 3D printing technologies for the development of
                                                                  biphasic porous scaffolds enabling spatiotemporal control
            Data  is  available  from  the  corresponding  author  upon   in tumor ablation and osteochondral regeneration.  Bioact
            reasonable request.                                   Mater. 2024;34:338-353.
                                                                  doi: 10.1016/j.bioactmat.2023.12.020
            References                                         12.  Li  S,  Zheng  W,  Deng  W,  et  al. Logic‐based strategy  for
                                                                  spatiotemporal  release  of dual extracellular vesicles  in
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                                                                  UY. Controlled release technologies for chronotherapy:
            2.   He Y, Li Z, Alexander PG, et al. Pathogenesis of osteoarthritis:   current status  and future  perspectives.  Curr Pharm Des.
               risk factors, regulatory pathways in chondrocytes, and   2023;29(14):1069-1091.



            Volume 10 Issue 5 (2024)                       213                                doi: 10.36922/ijb.3229
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