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International Journal of Bioprinting                                  Printing organoids in peptide matrices




            culture and bioprinting applications. These findings   Data availability
            contribute  valuable  insights  into  advancing  organoid   The original data are available from the authors
            research, bioprinting technology, and their implications   upon request.
            for  CRC modeling  and therapeutic  development in
            regenerative medicine.
                                                               References
            Acknowledgments                                    1.   Alsanea N, Abduljabbar AS, Alhomoud S, et al. Colorectal

            The authors would like to acknowledge KAUST’s         cancer in Saudi Arabia: incidence, survival, demographics
            Bioscience  and  Imaging  Core  Labs  for  supporting  the   and implications for national policies.  Ann  Saudi  Med.
            biological characterization and microscopy analyses.  2015;35(3):196-202.
                                                                  doi: 10.5144/0256-4947.2015.196
            Funding                                            2.   Alsanea N, Almadi MA, Abduljabbar AS, et al. National
                                                                  Guidelines for Colorectal Cancer Screening in Saudi Arabia
            This work was financially supported by KAUST: Seed    with strength of recommendations and quality of evidence.
            Fund Grant and Innovation Fund by KAUST’s Innovation   Ann Saudi Med. 2015;35(3):189-195.
            and Economic Development; and funding from the        doi: 10.5144/0256-4947.2015.189
            Computational Bioscience Research Center, KAUST.   3.   Favoriti P, Carbone G, Greco M, Pirozzi F, Pirozzi RE,
                                                                  Corcione F. Worldwide burden  of colorectal cancer: a
            Conflict of interest                                  review. Updates Surg. 2016;68(1):7-11.
                                                                  doi: 10.1007/s13304-016-0359-y
            The authors declare no conflicts of interest.
                                                               4.   Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal
            Author contribution                                   A. Global cancer statistics 2018: GLOBOCAN estimates of
                                                                  incidence and mortality worldwide for 36 cancers in 185
            Conceptualization: Rosario Pérez-Pedroza, Charlotte A.   countries. CA Cancer J Clin. 2018;68(6):394-424.
               E. Hauser                                          doi: 10.3322/caac.21492
            Data  curation:  Rosario Pérez-Pedroza, Jiayi Xu, Diana   5.   Vu JV, Sommovilla J. The molecular genetics of colorectal
               Eveline Sanchez-Amador, Manola Moretti, Alexander   cancer, hereditary colorectal cancer syndromes, and early-
               Valle-Perez, Antonio Cárdenas-Calvario, Dana       onset colorectal cancer.  Digest Dis Interv. 2023;07(01):
               Alhattab, Jezabel Parra-Garcia, Charlotte A. E. Hauser  058-070.
            Formal analysis: Jiayi Xu                             doi: 10.1055/s-0042-1757325
            Investigation: Rosario Pérez-Pedroza, Jiayi Xu, Diana   6.   Kim SE, Paik HY, Yoon H, Lee JE, Kim N, Sung MK. Sex-
               Eveline Sanchez-Amador, Manola Moretti, Alexander   and gender-specific disparities in colorectal cancer risk.
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               Alhattab, Jezabel Parra-Garcia                     doi: 10.3748/wjg.v21.i17.5167
            Methodology: Rosario Pérez-Pedroza, Manola Moretti  7.   Guinney J, Dienstmann R, Wang X, et al. The consensus
            Resources: Charlotte A. E. Hauser                     molecular subtypes of colorectal cancer.  Nat Med.
            Supervision: Rosario Pérez-Pedroza,  Manola Moretti,   2015;21(11):1350-1356.
               Charlotte A. E. Hauser                             doi: 10.1038/nm.3967
            Validation: Rosario Pérez-Pedroza, Jiayi Xu, Diana Eveline   8.   Sepulveda AR, Hamilton SR, Allegra CJ, et al. Molecular
               Sanchez-Amador, Manola Moretti, Alexander Valle-   biomarkers for the evaluation of colorectal cancer: guideline
               Perez, Antonio Cárdenas-Calvario, Dana Alhattab,   from the American Society for Clinical Pathology, College
               Jezabel Parra-Garcia, Charlotte A. E. Hauser       of American Pathologists, Association for Molecular
            Writing – original draft: Jiayi Xu, Rosario Pérez Pedroza  Pathology, and the American Society of Clinical Oncology. J
            Writing – review & editing: Rosario Pérez-Pedroza, Manola   Clin Oncol. 2017;35(13):1453-1486.
               Moretti, Charlotte A. E. Hauser                    doi: 10.1200/JCO.2016.71.9807
                                                               9.   Lipkin M, Reddy B, Newmark H, Lamprecht SA. Dietary
            Ethics approval and consent to participate            factors  in  human  colorectal  cancer.  Annu Rev Nutr.
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            Not applicable.                                       doi: 10.1146/annurev.nutr.19.1.545

            Consent for publication                            10.  Labianca R, Beretta GD, Kildani B, et al. Colon cancer. Crit
                                                                  Rev Oncol Hematol. 2010;74(2):106-133.
            Not applicable.                                       doi: 10.1016/j.critrevonc.2010.01.010



            Volume 10 Issue 5 (2024)                       359                                doi: 10.36922/ijb.3033
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