Page 388 - IJB-10-5

International Journal of Bioprinting Tunable anisotropic gyroid bioscaffolds

and in vitro cellular responses were investigated. It was Ethics approval and consent to participate
observed that an increase in the aspect ratio of the unit
cell significantly amplified the anisotropic mechanical Not applicable.
properties of the gyroid structure. However, this Consent for publication
modification slightly reduced cell proliferation efficiency
in comparison to the uniform gyroid structure, which Not applicable.
can be attributed to variations in Gaussian curvatures.
This study presented an effective design methodology Availability of data
for TPMS, including but not limited to gyroid structures, Data is available from the corresponding author upon
with tailored properties. Our methodology can be reasonable request.
extended to the design of smart scaffolds incorporating
piezoelectric materials for bone implants beyond References
traditional materials.
1. Vijayavenkataraman S, Kuan LY, Lu WF. 3D-printed
Acknowledgments ceramic triply periodic minimal surface structures for
design of functionally graded bone implants. Mater Design.
The authors gratefully acknowledge the support from 2020;191:108602.
U3DP of The Hong Kong Polytechnic University, and doi: 10.1016/j.matdes.2020.108602
extend special thanks to Tab Cheng and Sidney Wong for 2. Yan C, Hao L, Hussein A, Young P. Ti–6Al–4V triply
their valuable assistance. periodic minimal surface structures for bone implants
fabricated via selective laser melting. J Mech Behav Biomed
Funding Mater. 2015;51:61-73.
doi: 10.1016/j.jmbbm.2015.06.024
The work described in this paper was mainly supported
by the funding support to the State Key Laboratories 3. Dong Z, Zhao X. Application of TPMS structure in bone
in Hong Kong from the Innovation and Technology regeneration. Eng Regen. 2021;2(8):154-162.
doi: 10.1016/j.engreg.2021.09.004
Commission (ITC of the Government of the Hong Kong
Special Administrative Region [HKSAR] of China), 4. Shan Y, Bai Y, Yang S, et al. 3D-printed strontium-
and The Hong Kong Polytechnic University (Project incorporated β-TCP bioceramic triply periodic minimal
Code: BBX2 and PolyU Project Code: 1-BBTN) and a surface scaffolds with simultaneous high porosity,
enhanced strength, and excellent bioactivity. J Adv Ceram.
grant from the Research Committee of The Hong Kong 2023;12(9):1671-1684.
Polytechnic University under project account code doi: 10.26599/JAC.2023.9220787
G-UAMY.
5. Al‐Ketan O, Abu Al‐Rub RK. MSLattice: a free software for
Conflict of interest generating uniform and graded lattices based on triply periodic
minimal surfaces. Mater Des Process Commun. 2021;3(6):e205.
The authors declare they have no competing interests. doi: 10.1002/mdp2.205
6. Ma S, Song K, Lan J, Ma L. Biological and mechanical
Author contributions property analysis for designed heterogeneous porous
scaffolds based on the refined TPMS. J Mech Behav Biomed
Conceptualization: Ka-Wai Yeung, Chak-Yin Tang Mater. 2020;107:103727.
Data curation: Ka-Wai Yeung, Chi-Yeung Mang, doi: 10.1016/j.jmbbm.2020.103727
Quan-Jing Mei
Funding acquisition: Chak-Yin Tang 7. Yang Y, Xu T, Bei H-P, et al. Gaussian curvature–driven
direction of cell fate toward osteogenesis with triply
Investigation: Ka-Wai Yeung, Quan-Jing Mei periodic minimal surface scaffolds. Proc Natl Acad Sci U S
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Supervision: Chak-Yin Tang doi: 10.1073/pnas.2206684119
Visualization: Ka-Wai Yeung 8. Deering J, Dowling KI, DiCecco L-A, McLean GD, Yu B,
Writing – original draft: Ka-Wai Yeung Grandfield K. Selective Voronoi tessellation as a method to
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Zhenjia Huang doi: 10.1016/j.jmbbm.2021.104361

Volume 10 Issue 5 (2024) 380 doi: 10.36922/ijb.3609