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International Journal of Bioprinting                                 Fluid mechanics of extrusion bioprinting
























































            Figure 13. Chaotic multi-material printing using the various number of inlets and helical mixing elements; (A) design of head with axial inlets, (B)
            predictions of internal multi-layer structure inside fiber by computational simulations, (C) multi-layer structures inside the fibers printed with different
            numbers of mixing elements and axial inlets, and (D) computational simulation results for the case with three mixing elements. Abbreviation: CFD,
            computational fluid dynamics. Reprinted with permission from ref.  Copyright © 2023 Wiley‐VCH GmbH.
                                                       169



            is applied on solid walls. Some polymer solutions or melts   where η  denotes the apparent viscosity of the fluid at
                                                                        app
                                                               the solid wall, τ  is wall shear stress, and δ  is the thickness
            may exhibit slip on the solid wall. It should be examined      w                    t
                                                               of the slip layer. The solution of  Equations XXVII and
            by performing steady shear tests with different gaps using   XXVIII requires a constitutive relation to relate the stress
                                                                     =
                                                                                            =
            a parallel plate rheometer.  Based on a power-law fluid   tensor (τ ) to the strain rate tensor (γ ); it could be one of
                                 78
                                                               the models described in Table 3.
            model, the slip condition can be written as :
                                              176
                                                                   Numerical  simulations  of  the  bioprinting process
                                                               have primarily focused on understanding the flow of
                                                               biomaterials within the bioprinter head. CFD simulations
                             δτ 1/ n                           have been employed to examine the impact of parameters
                        U slip =  tw n           (XXXVIII)     related to the dispensing system in two main areas. One
                               1/
                              η app
            Volume 10 Issue 6 (2024)                       139                                doi: 10.36922/ijb.3973
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