Page 311 - IJB-10-6

International Journal of Bioprinting Bioprinted plasma biocarriers for MSC delivery

Figure 1. Protein–protein interactions and biological functions of growth factors and chemokines used in PRP biocarrier functionalization. (A) Key
growth factors (GFs) and cytokines used for biocarrier functionalization using platelet-rich plasma (PRP), highlighting protein–protein interactions and
three molecular clusters. (B) Principal chemokines utilized to dope the PRP biocarrier and their interactions. (C) Enriched biological processes involving
molecules described in (A). (D) Main biological functions associated with the chemokine cluster. False Discovery Rate (FDR) indicates the significance of
biological enrichment, with p-values corrected for multiple testing using the Benjamini–Hochberg procedure.

and inflamed PRP biocarriers against nude biocarriers Inc., https://digitalinsights.qiagen.com/IPA, accessed on
or inflamed nude biocarriers, calculating fold changes in May 2024; Qiagen, Germany), which incorporates nearly
protein expression. 5 million curated findings from experimental settings and
Data from the multiplexing platform were analyzed third-party databases. IPA® algorithms predicted signaling
using Ingenuity Pathway Analysis Software (IPA®; QIAGEN pathways and canonical pathways, with the core analysis

Volume 10 Issue 6 (2024) 303 doi: 10.36922/ijb.4426