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International Journal of Bioprinting                               3D-printed scaffold for biomolecule delivery




            Conflict of interest                                  adhesion mechanism. Eur Cell Mater. 2014;28:387-403.
                                                                  doi: 10.22203/ecm.v028a27
            The authors have no competing interests to declare.
                                                               7.   Shah NJ, Hyder MN, Quadir MA, et al. Adaptive growth
            Author contributions                                  factor delivery from a polyelectrolyte coating promotes
                                                                  synergistic bone tissue repair and reconstruction. Proc Natl
            Conceptualization: Jong-Eun Won, Hae-Won Kim          Acad Sci USA. 2014;111(35):12847-12852.
            Formal analysis: Jong-Eun Won, Hyun Kyung Moon        doi: 10.1073/pnas.1408035111
            Investigation: Jong-Eun Won                        8.   Kuttappan S, Mathew D, Jo JI, et al. Dual release of growth
            Methodology: Jong-Eun Won                             factor from nanocomposite fibrous scaffold promotes
            Writing – original draft: Jong-Eun Won, Ji Suk Shim   vascularisation and bone regeneration in rat critical sized
            Writing – review & editing:  Jong-Eun Won, Hae-Won Kim,   calvarial defect. Acta Biomater. 2018;78:36-47.
               Ji Suk Shim                                        doi: 10.1016/j.actbio.2018.07.050
                                                               9.   Barnes GL, Kostenuik PJ, Gerstenfeld LC, Einhorn TA.
            Ethics approval and consent to participate            Growth factor regulation of fracture repair.  J  Bone  Miner
            This work was approved by Animal Care and Use         Res. 1999;14(11):1805-1815.
            Committee of the Korea University (KOREA-2021-0004).      doi: 10.1359/jbmr.1999.14.11.1805
            All necessary ethical guidelines have been followed, and   10.  Termaat MF, Den Boer FC, Bakker FC, Patka P, Haarman
            relevant documentation is available upon request.     HJ. Bone morphogenetic proteins. Development and clinical
                                                                  efficacy in the treatment of fractures and bone defects.
            Consent for publication                               J Bone Joint Surg Am. 2005;87(6):1367-1378.
                                                                  doi: 10.2106/JBJS.D.02585
            Not applicable.
                                                               11.  Cochran DL, Jones AA, Lilly LC, Fiorellini JP, Howell H.
            Availability of data                                  Evaluation of recombinant human bone morphogenetic
                                                                  protein-2  in  oral  applications  including  the  use  of
            Data  is  available  from  the  corresponding  author  upon   endosseous  implants:  3-year  results  of  a  pilot  study  in
            reasonable request.                                   humans. J Periodontol. 2000;71(8):1241-1257.
                                                                  doi: 10.1902/jop.2000.71.8.1241
            References                                         12.  Epstein SE, Fuchs S, Zhou YF, Baffour R, Kornowski
                                                                  R. Therapeutic interventions for enhancing collateral
            1.   Hussey GS, Dziki JL, Badylak SF. Extracellular matrix-  development by administration of growth factors: basic
               based materials for regenerative medicine. Nat Rev Mater.   principles, early results and potential hazards.  Cardiovasc
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               doi: 10.1038/s41578-018-0023-x                     doi: 10.1016/s0008-6363(00)00217-0
            2.   Won JE, Lee YS, Park JH, et al. Hierarchical microchanneled   13.  Freeman  FE, Pitacco  P,  van Dommelen  LHA, et  al.  3D
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               doi: 10.1016/j.biomaterials.2019.119548            doi: 10.1126/sciadv.abb5093
            3.   Babensee JE, McIntire LV, Mikos AG. Growth factor delivery   14.  Oliveira ER, Nie L, Podstawczyk D, et al. Advances in
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               doi: 10.1023/a:1007502828372                       Mol Sci. 2021;22(2):903-935.
            4.   Wang ZM, Wang ZF, Lu WW, Zhen WX, Yang DZ, Peng SL.      doi: 10.3390/ijms22020903
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            6.   Kang J, Park HM, Kim YW, et al. Control of mesenchymal   J Periodontal Res. 2020;55(5):694-704.
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            Volume 10 Issue 6 (2024)                       454                                doi: 10.36922/ijb.4638
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