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International Journal of Bioprinting                           3D bioprinting techniques & hydrogels materials




                                                                                               (Continued)
                 Ref.  40  178  179  180  183  184  189  195  196    198     199  215   219







                    In vitro: BMSCs  In vivo: Rabbits  In vitro: hTMSCs  In vivo: Rabbit OCDs  In vitro: hMSCs  In vitro: BMSCs  In vivo: Rat OCDs  In vitro: BMSCs  In vivo: Rat OCDs  In vitro: MSCs  In vivo: Rat OCDs  In vitro: ASC spheres  In vivo: Rabbit OCDs  In vitro: MSCs;   chondrocytes  In vitro: Osteoblast  In vivo: Rat tibia defect  In vitro: BMSCs  In vivo: Mouse  subcutaneous implantation;   In vitro: ACPCs; BMSCs  In vivo: Rabbit OCDs  In vitro: Rat BMSCs  In


                 Model                                                  goat OCDs




                    Promote the polarization of M2 macrophages;  promote osteochondral regeneration  Promote osteochondral regeneration Promote early differentiation of hMSCs; excellent  osteogenic and cartilage differentiation ability Create nHA gradients; promote osteochondral  Promote type II collagen and inhibit interleukin-1β;  promote osteochondral regeneration; promote the  Improve the vascularization level in the core area of  bone defect; promote osteochondral re














                 Effects            regeneration  deposition of ECM protein  differentiation.  regeneration



             Table 4. Application of 3D-printed bioactive hydrogels in osteochondral repair.

                 Crosslinking method  N/A  N/A   Chemical (photo-crosslinked)  Physical (CaCl 2 )  Chemical  Physical  Chemical  Physical  Chemical (photo-crosslinked)  Chemical  Chemical (photo-crosslinked)  Chemical (UV-radiation)  Chemical (photo-crosslinked)












                 Bioactive factor  PRP  hTMSCs  hMSCs  BMSCs  BMSCs  MSCs  ASCs spheres  Chondroprogenitor cells  Osteoblasts  BMSCs; FPSCs;   Chondrocytes  ACPCs; BMSCs  MSCs-derived exos; dECM  ECM; MSCs-derived exos








                 Hydrogel composition  GelMA   Atelocollagen; HA   PEG-GelMA   nHA  PCL; KGN; β-TCP; DC; HeMA   GelMA   NIPAM; SBMA  Bioceramic; polymers; GelMA   PEGDA; XLG nanoclay; HA   PCL; PLA; PLGA; alginate  GelMA; alginate   HA-DA; oxidized HA; GelMA  GelMA











            Volume 10 Issue 6 (2024)                        82                                doi: 10.36922/ijb.4472
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