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International Journal of Bioprinting 3D bioprinting techniques & hydrogels materials
(Continued)
Ref. 40 178 179 180 183 184 189 195 196 198 199 215 219
In vitro: BMSCs In vivo: Rabbits In vitro: hTMSCs In vivo: Rabbit OCDs In vitro: hMSCs In vitro: BMSCs In vivo: Rat OCDs In vitro: BMSCs In vivo: Rat OCDs In vitro: MSCs In vivo: Rat OCDs In vitro: ASC spheres In vivo: Rabbit OCDs In vitro: MSCs; chondrocytes In vitro: Osteoblast In vivo: Rat tibia defect In vitro: BMSCs In vivo: Mouse subcutaneous implantation; In vitro: ACPCs; BMSCs In vivo: Rabbit OCDs In vitro: Rat BMSCs In
Model goat OCDs
Promote the polarization of M2 macrophages; promote osteochondral regeneration Promote osteochondral regeneration Promote early differentiation of hMSCs; excellent osteogenic and cartilage differentiation ability Create nHA gradients; promote osteochondral Promote type II collagen and inhibit interleukin-1β; promote osteochondral regeneration; promote the Improve the vascularization level in the core area of bone defect; promote osteochondral re
Effects regeneration deposition of ECM protein differentiation. regeneration
Table 4. Application of 3D-printed bioactive hydrogels in osteochondral repair.
Crosslinking method N/A N/A Chemical (photo-crosslinked) Physical (CaCl 2 ) Chemical Physical Chemical Physical Chemical (photo-crosslinked) Chemical Chemical (photo-crosslinked) Chemical (UV-radiation) Chemical (photo-crosslinked)
Bioactive factor PRP hTMSCs hMSCs BMSCs BMSCs MSCs ASCs spheres Chondroprogenitor cells Osteoblasts BMSCs; FPSCs; Chondrocytes ACPCs; BMSCs MSCs-derived exos; dECM ECM; MSCs-derived exos
Hydrogel composition GelMA Atelocollagen; HA PEG-GelMA nHA PCL; KGN; β-TCP; DC; HeMA GelMA NIPAM; SBMA Bioceramic; polymers; GelMA PEGDA; XLG nanoclay; HA PCL; PLA; PLGA; alginate GelMA; alginate HA-DA; oxidized HA; GelMA GelMA
Volume 10 Issue 6 (2024) 82 doi: 10.36922/ijb.4472

