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Duan, et al.
2. Methodology data analysis was performed to look for probability
centers with the aid of normal distribution by age and
2.1. The research strategy of this study body weight. The cases nearest to the mean value in each
We confirmed that the research involving experiments on subregion were selected. These overlapping cases are the
human subjects met the ethical standards of the Helsinki target cases for convex-concave 3D printing. Finally, the
Declaration in 1975. The research was approved by the transparent concave 3D models were precisely measured
Ethics Committee of Beijing Children’s Hospital, Capital to obtain the important parameters for BB design infants
Medical University. All infants’ parents had informed and only, to complete the design of BB, to generate the sample,
signed the consents. First-two-dimensional CT airway and to verify the blocking effect of produced sample in
[14]
reconstructions of 124 normal infants (non-premature) transparent concave 3D models (Figure 4) .
aged 5–390 days were selected from Beijing Children’s 2.2. Statistical analysis of data: Linear fitting
Hospital medical image database. The following key data
are measured under a computer program: (i) TD: The and goodness-of-fit test
diameter of the right main bronchus for designing TD Multivariate analysis was used to identify correlations between
of inflatable cuff; (ii) LD: The distance from the upper the continuous numeric data , including the association
[15]
margin of RUL opening to carina for designing LD of between the sex, age, weight of the patient and GC, TD, and
inflatable cuff; and (iii) G-C: The distance from glottis to LD of their CT airway reconstructions. Standard least squares
carina for determining length of the catheter body. Second, regression was used with log transformation [16,17] .

Figure 4. The research strategy of this study.

International Journal of Bioprinting (2022)–Volume 8, Issue 3 33