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Silk Fibroin and Calcium Phosphate 3D Scaffolds Promote in vitro Osteogenesis
A B

C D

E F

G

Figure 4. Tensile and compression mechanical properties of dry SF scaffolds. (A) Stress-strain curves of different monofilaments. (B) Tensile
modulus of different monofilaments. (C) Compressive stress-strain curves of various scaffolds. (D) Compressive modulus of various scaffolds.
(E) Compressive stress-strain curves of mineralized SF scaffolds from Ink 3 at various pH conditions. (F) Derived compressive modulus from
the initial linear region 1% to 3% of the curves in (E). (G) Relationship between compressive modulus and mineralization times of scaffolds
mineralized in methanol solution. Significant differences are denoted as: * for P<0.05; ** for 0.01<P<0.05; *** for 0.001<P<0.01.
phase was proven stiffer and stronger than DCP . Thus, – 11 resulted in hybrid SF scaffolds with significantly
[52]
as shown in Figure 4E and F, mineralization at pH 10 reduced compression modulus and strength.
10 International Journal of Bioprinting (2022)–Volume 8, Issue 4