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Ghosh and Yi
is not widely practiced due to a shortage of custom plant References
bioinks. Significant contributions of worldwide in the
development of optimal bioinks present the opportunity 1. Mobaraki M, Ghaffari M, Yazdanpanah A, et al., 2020,
for commercialized bioprinting technology and bioink in Bioinks and Bioprinting: A Focused Review. Bioprinting,
the future, which can be used in many fields, especially 18:e00080.
plant biology, for educational and industrial applications. https://doi.org/10.1016/j.bprint.2020.e00080
In the future, the use of other materials and print heads 2. Donderwinkel I, Van Hest JC, Cameron NR, 2017, Bio-inks
to make more complex structures should be studied—
for example, drug-filled microspheres can be added to for 3D Bioprinting: Recent Advances and Future Prospects.
bioinks to improve stem cell differentiation, survival, Polym Chem, 8:4451–71.
and cell viability [167] . Advancement in the understanding 3. Gopinathan J, Noh I, 2018, Recent Trends in Bioinks for 3D
of plant morphology, function, and behavior is urgently Printing. Biomater Res, 22:11.
needed to ensure future global food security, which https://doi.org/10.1186/s40824-018-0122-1
necessitates technological advancement such as 4. Guvendiren M, Molde J, Soares RM, et al., 2016, Designing
bioprinted plants Although 3D printing in plant science
remains in preliminary stages, the previous studies have Biomaterials for 3D Printing. ACS Biomater Sci Eng,
demonstrated its potential for advancing plant science. 2:1679–93.
As 3D printing technology becomes more affordable https://doi.org/10.1021/acsbiomaterials.6b00121
and available, it will improve research coordination and 5. Gungor-Ozkerim PS, Inci I, Zhang YS, et al., 2018, Bioinks
scientific methodology , and advance plant science for 3D Bioprinting: An Overview. Biomater Sci, 6:915–46.
[31]
and growth systems. Designs that are useful to plant https://doi.org/10.1039/c7bm00765e
scientists could be easily obtained using 3D printing
without the need to be made commercially available. 6. Parak A, Pradeep P, du Toit LC, et al., 2019, Functionalizing
As this technology evolves in plant science, an open- Bioinks for 3D Bioprinting Applications. Drug Discov Today,
source approach may be necessary for collective model 24:198–205.
improvement and adapting useful models to different https://doi.org/10.1016/j.drudis.2018.09.012
plant systems. Thus, it is evident that in the field of 7. Mironov V, 2003, Printing Technology to Produce Living
bioprinting, encapsulating plant cells in biomaterials to Tissue. Expert Opin Biol Ther, 3:701–4.
create a bioink formulation could be effective in treating
a wide range of human and other animal illnesses. https://doi.org/10.1517/14712598.3.5.701
In addition, bioprinted plant cells can facilitate the 8. Mironov V, Markwald RR, Forgacs G, 2003, Organ Printing:
understanding of plant cell paracrine effects in in vitro Self-Assembling Cell Aggregates as “Bioink”. Sci Med,
models of human and animal diseases. 9: 69–71.
In conclusion, the development and improvement 9. Groll J, Burdick JA, Cho DW, et al., 2018, A Definition
of various bioinks is one of the primary paths for the of Bioinks and their Distinction from Biomaterial Inks.
advancement of green bioprinting. A greater diversity
of bioinks will lead to a larger scope for green Biofabrication, 11:013001.
bioprinting. https://doi.org/10.1088/1758-5090/aaec52
10. Muthukrishnan L, 2021, Imminent Antimicrobial Bioink
Funding Deploying Cellulose, Alginate, EPS and Synthetic Polymers

This study was financially supported by Chonnam for 3D Bioprinting of Tissue Constructs. Carbohydr Polym,
National University (Grant number: 2021-2474). This 260:117774.
work was also supported by the National Research 11. Wu D, Yue Y, Tan J, et al., 2018, 3D Bioprinting of Gellan
Foundation of Korea (NRF) grant funded by the Korea Gum and Poly (Ethylene Glycol) Diacrylate Based Hydrogels
government MSIT (No. 2020R1A5A8018367).
to Produce Human-scale Constructs with High-fidelity. Mater
Conflict of interest Des, 160:486–95.

No conflict of interest was reported. https://doi.org/10.1016/j.matdes.2018.09.040
12. Hu D, Wu D, Huang L, et al., 2018, 3D Bioprinting of Cell-
Author contributions Laden Scaffolds for Intervertebral Disc Regeneration. Mater
Conceptualization, investigation, writing-original draft, Lett, 223:219–22.
visualization, and review and editing: Susmita Ghosh 13. Crapo PM, Gilbert TW, Badylak SF, 2011, An Overview
Supervise and guide: Hee-Gyeong Yi of Tissue and Whole Organ Decellularization Processes.

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