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Mancilla-De-la-Cruz, et al.
Table 13. 3D printing technologies for implants
3D printing API Formulation Effect References
technology
Implant
Binder jetting Isoniazid, Poly D, L - lactic acid (PDLLA) Multiactive, sustained [105]
rifampicin release
Levofloxacin, Poly L - lactic acid (PLLA) Multiactive, controlled [106]
rifampicin release
Isoniazid Poly L-lactic acid (PLLA), acetone, Sustained release [107]
ethanol, water
Levofloxacin, Poly D, L - lactic acid (PDLLA) Multiactive, sustained [108]
tobramycin release
Levofloxacin Poly L-lactic acid (PLLA), ethanol, acetone Pulsed release profile [122]
Filament extrusion Nitrofurantoin Polylactic acid (PLA), hydroxypropyl Flexible dosing and [55]
methylcellulose (HPMC) precision medication
Nitrofurantoin Polylactic acid (PLA) Biofilm inhibition [109]
Gentamicin Polylactic acid (PLA) Hernia meshes [110]
Gentamicin, Polylactic acid (PLA) Drugs eluting product [111]
methotrexate
Niclosamide, Polycaprolactone (PCL), graphene Vascular stent [112]
inositol nanoplatelets (GR)
phosphate (IP6)
Ciprofloxacin Polylactic acid (PLA), Bone defect diseases [113]
hydrochloride nano-hydroxyapatite
Syringe extrusion Dexamethasone Strontium containing mesoporous Controlled ion release [27]
bioactive glass (Sr-MBG)
Isoniazid, Mesoporous silica nanoparticles (MSN), Multi-drug, osteoarticular [114]
rifampicin beta-tricalcium phosphate (B-TCP) tuberculosis therapy
Doxorubicin Polycaprolactone (PCL), mesoporous Local anticancer and [115]
bioactive glass (MBG), Fe O 4 enhanced osteogenic
3
activity, and magnetic
hyperthermia
Dimethyloxallyl Mesoporous bioactive glass (MBG), poly Composite scaffold [116]
glycine (3-hydroxybutyrate-co-3- hydroxyhexanoate)
Vascular Calcium phosphate cement (CPC), Bone defect healing [117]
endothelial alginate, alginate-gellan gum
growth factor
Ciprofloxacin Polylactic acid (PLA), nano-hydroxyapatite Controlled [118]
(n-HA), Hydroxypropyl cellulose antibacterial release
(HPC-M), Microcrys- talline cellulose
Pharmacel 101 (MCC PH 101).
Amikacin sulfate Polylactic acid (PLA), Local drug delivery [119]
nano-hydroxyapatite (n-HA)
Stereolithography Recombinant Polypropylene fumarate (PPF), carbonate, Delayed release [121]
human bone hydroxyapatite, polylactic-co-glycolic acid
morphogenetic (PLGA) microspheres, collagen
protein 2
(rhBMP-2)
Lidocaine Gelucire Sustained and [123]
hydrochloride localized delivery
Selective laser Doxorubicin, Ti6Al4V, ethylene glycol Bone cancer therapy [120]
melting apoptosis-
inducing ligand
(Apo2L/TRAIL)

International Journal of Bioprinting (2022)–Volume 8, Issue 4 337