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Mancilla-De-la-Cruz, et al.
           tissue engineering, and medical devices . Future trends   Information collection,  data analysis, graphics and
                                            [10]
           envision a revolution in pharmacy in the next years, and   writing – original draft: Jessica Mancilla-De-la-Cruz
           science and technology advances will enable 3D printing   Review, vetting and editing: Jia An, Chee Kai Chua
           of innovative drug delivery systems.
                                                               Ethics approval and consent to participate
           6. Conclusions
                                                               Not applicable.
           3D printing technology is evolving quickly providing
           a new way to develop attractive solutions for medical   Consent for publication
           applications [148] . Medication administration is being   Not applicable.
           revolutionized, and researchers, doctors and patients become
           increasingly interested in having alternatives that are more   Availability of data
           efficient  and  friendly.  At  present,  standardized  doses  of
           medicines predominate but each patient requires unique   Not applicable.
           treatments with tailored dosages. The DDDs fabricated by   References
           3D printing enable the production of personalized drugs for
           the patients with specific needs. Moreover, this technology   1.   Florence, A, Attwood, D 2015, Physiochemical Principles of
           has unique capabilities to work with complex geometries,   Pharmacy. London: Pharmaceutical Press.
           high precision, and multiple APIs.
               In  this  review,  the  potential  uses of  3D printing   2.   Kleiner L, Wright J, Wang Y, 2014, Evolution of Implantable
           technology are detailed, as well as the different techniques   and Insertable Drug  Delivery Systems.  J  Control Release,
           that have been developed along with their challenges and   181:1–10.
           application in drug delivery is identified. Materials used      https://doi.org/10.1016/j.jconrel.2014.02.006
           were also determined through three principal categories:   3.   Hoffman  A,  Hillery  A,  2017,  Historical  Introduction  to
           polymers, glasses and hydrogels. In addition, five dosage   the Field of Controlled Drug Delivery. Drug Delivery
           forms were identified: (i) Oral drug dosage, (ii) topical
           dosage form, (iii)  rectal  and vaginal,  (iv) parenteral   Fundamental Appllications. United States: CRC Press. p1–21.
           dosage form, and (v) implants. The API, formulation and   4.   Deanesly R, Parkes A, 1937, Biological Properties of Some
           effect are discussed for all cases.                     New Derivatives of Testosterone. Biochem J, 31:1161–4.
               3D printing  will  revolutionize  the  concept  of      https://doi.org/10.1042/bj0311161
           traditional manufacturing by innovatively adding value   5.   Schork NJ, 2015, Personalized Medicine:  Time  for one-
           to health applications, such as drug delivery. A  radical   Person Trials. Nature, 520:609–11.
           change in medical treatments will happen in the coming      https://doi.org/10.1038/520609a
           years.
                                                               6.   Peak R, 2018, Precision Medicine is not Just Genomics: The
           Acknowledgments                                         right dose for every patient.  Ann Rev Pharmacol Toxicol,

           We  acknowledge  Tecnologico  de  Monterrey  and        58:105–22.
           CONACYT for their support.                              https://doi.org/10.1146/annurev-pharmtox-010617-052446
                                                               7.   Prasad L, Smyth H, 2016, 3D Printing Technologies for Drug
           Funding                                                 Delivery: A Review. Drug Dev Ind Pharm, 42:1019–31.

           The authors acknowledge institutional funding received      https://doi.org/10.3109/03639045.2015.1120743
           from Tecnologico de Monterrey and Consejo Nacional de   8.   Syrkel M, 2021, A Brief History of Additive Manufacturing.
           Ciencia y Tecnología (CONACyT) through a Graduate       Arizona: Nexus 3 Manufacturing and Engineering. Available
           Studies  Scholarship  and  an  Academic  Scholarship  as   from:  https://www.nexus3mfg.com/3d-printing  [Last
           member of the National System of Researchers (Sistema
           Nacional de Investigadores).                            accessed on 2021 Apr 06].
                                                               9.   International  Organization  for Standardization/ASTM
           Conflict of interest                                    52900, 2021,  Additive  Manufacturing-General  Principles-
           The authors declare that they have no conflicts of interest.  Fundamentals and  Vocabulary. Switzerland:  International
                                                                   Organization  for Standardization.  Available  from:  https://
           Author contributions                                    Www.Iso.Org/Obp/Ui/Iso: Std:Iso-Astm:52900:Ed-2:V1:En

           Conceptualization, Methodology, Supervision, writing –   10.  Jamroz W, Szafraniec J, Kurek M, et al., 2018, 3D Printing
              review & editing: Marisela Rodriguez-Salvador        in  Pharmaceutical  and Medical  Applications-Recent

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